Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2023; 11(22): 5329-5337
Published online Aug 6, 2023. doi: 10.12998/wjcc.v11.i22.5329
Hepatoid adenocarcinoma of the stomach with neuroendocrine differentiation: A case report and review of literature
He Fei, Ze-Feng Li, Ying-Tai Chen, Dong-Bing Zhao
He Fei, Ze-Feng Li, Ying-Tai Chen, Dong-Bing Zhao, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Author contributions: Chen YT and Zhao DB designed the research study; Fei H contributed to manuscript writing and editing; Li ZF reviewed the pathological sections; All authors wrote the manuscript; All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dong-Bing Zhao, MD, Surgeon, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. dbzhao@cicams.ac.cn
Received: April 25, 2023
Peer-review started: April 25, 2023
First decision: June 12, 2023
Revised: June 24, 2023
Accepted: July 17, 2023
Article in press: July 17, 2023
Published online: August 6, 2023
Processing time: 100 Days and 8.4 Hours
Core Tip

Core Tip: Hepatoid adenocarcinoma of the stomach (HAS) with neuroendocrine differentiation (NED) is rare histological subtype. We first reported the detailed processes of surgery and chemotherapy of HAS with NED and the survival time was 27 mo combined with postoperative chemotherapy, which provided an important reference for clinical diagnosis and treatment of this condition.