Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 26, 2022; 10(9): 2916-2922
Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2916
Local hyperthermia combined with chemotherapy for the treatment of multiple recurrences of undifferentiated pleomorphic sarcoma: A case report
Yi-Ting Zhou, Ruo-Yu Wang, Yao Zhang, Dong-Yi Li, Jian Yu
Yi-Ting Zhou, Jian Yu, Hyperthermia Center, The Affiliated Zhongshan Hospital of Dalian University, Dalian 110006, China
Ruo-Yu Wang, Department of Medical Oncology, The Affiliated Zhongshan Hospital of Dalian University, Dalian 110006, China
Yao Zhang, Dong-Yi Li, Department of Bone and Soft Tissue Oncology, The Affiliated Zhongshan Hospital of Dalian University, Dalian 110006, China
Author contributions: Zhou YT and Yu J were the patient’s medical oncologists, reviewed the literature and drafted the manuscript; Zhang Y and Li DY were the patient’s surgeons, performed the surgery and analyzed the results; Wang RY analyzed and interpreted the imaging findings, reviewed the literature and drafted the manuscript; Wang RY and Yu J were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Yu, MMed, Chief Doctor, Professor, Hyperthermia Center, Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Dalian 110006, China. dlyujian1127@163.com
Received: October 6, 2021
Peer-review started: October 6, 2021
First decision: December 10, 2021
Revised: December 19, 2021
Accepted: February 15, 2022
Article in press: February 15, 2022
Published online: March 26, 2022
Processing time: 167 Days and 4.6 Hours
Core Tip

Core Tip: Undifferentiated pleomorphic sarcoma is a type of soft tissue sarcoma, but the histologic origin and direction of differentiation are still unclear. Patients with locally advanced, unresectable, or metastatic disease have a poor prognosis, and there are few treatment options available. Clinically, local hyperthermia combined with chemotherapy can be used to achieve surgical R0 resection in this type of patient.