Han YH, Jeong HJ, Kang HG, Lim ST. Incidental accumulation of Technetium-99m pertechnetate in subacute cerebral infarction: A case report. World J Clin Cases 2022; 10(23): 8400-8405 [PMID: 36159510 DOI: 10.12998/wjcc.v10.i23.8400]
Corresponding Author of This Article
Seok Tae Lim, PhD, Professor, Department of Nuclear Medicine, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jounbuk National University Medical School and Hospital, 20 Geonjiro Deokjin-gu, Jeonju 54907, Jeonbuk, South Korea. stlim@jbnu.ac.kr
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yeon-Hee Han, Hwan-Jeong Jeong, Seok Tae Lim, Department of Nuclear Medicine, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jounbuk National University Medical School and Hospital, Jeonju 54907, Jeonbuk, South Korea
Hyun Goo Kang, Department of Neurology, Jeonbuk National University Medical School and Hospital, Jeonju 54907, Jeonbuk, South Korea
Author contributions: Han YH and Lim ST were nuclear physicians, performed the conceptualization, investigation, and contributed to manuscipt drafting; Jeong HJ reviewed the literature and contributed to manuscript editing; Kang HG was a neurophysician and performed the disease consultation and manuscript drafting; Han YH and Lim ST were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Seok Tae Lim, PhD, Professor, Department of Nuclear Medicine, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jounbuk National University Medical School and Hospital, 20 Geonjiro Deokjin-gu, Jeonju 54907, Jeonbuk, South Korea. stlim@jbnu.ac.kr
Received: April 5, 2022 Peer-review started: April 5, 2022 First decision: June 16, 2022 Revised: June 17, 2022 Accepted: July 5, 2022 Article in press: July 5, 2022 Published online: August 16, 2022 Processing time: 118 Days and 1.5 Hours
Core Tip
Core Tip: Tc-99m pertechnetate is a truly carrier-free radiotracer transported by sodium iodide symporter. Salivary scintigraphy using Tc-99m pertechnetate is frequently performed for diagnosing salivary gland diseases such Sjogren's syndrome. Here, we present a rare case of Tc-99m pertechnetate accumulation in the subacute cerebral infarction lesion. The reason for Tc-99m pertechnetate accumulation is thought to be due to ingrowth and proliferation of new capillaries with enhanced permeability in the subacute cerebral infarction lesion. The present case highlights that Tc-99m pertechnetate could accumulate in a subacute cerebral infarction lesion. The mechanisms of an unexpected uptake of Tc-99m pertechnetate in unusual sites should be evaluated and kept in mind for better interpretation.
