Lin XQ, Chen YR, Chen X, Cai YP, Lin JX, Xu DM, Zheng XC. Impact of preoperative carbohydrate loading on gastric volume in patients with type 2 diabetes. World J Clin Cases 2022; 10(18): 6082-6090 [PMID: 35949825 DOI: 10.12998/wjcc.v10.i18.6082]
Corresponding Author of This Article
Xiao-Chun Zheng, MD, Professor, Department of Anesthesiology, Shenli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, No. 134 East Street, Fuzhou 350001, Fujian Province, China. zhengxiaochun2021@163.com
Research Domain of This Article
Anesthesiology
Article-Type of This Article
Randomized Clinical Trial
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Lin XQ, Chen YR, Chen X, Cai YP, Lin JX, Xu DM, Zheng XC. Impact of preoperative carbohydrate loading on gastric volume in patients with type 2 diabetes. World J Clin Cases 2022; 10(18): 6082-6090 [PMID: 35949825 DOI: 10.12998/wjcc.v10.i18.6082]
Xin-Qiang Lin, Department of Anesthesiology, Affiliated Hospital of Putian College, Putian Maternity and Child Care Hospital, Putian 351100, Fujian Province, China
Yu-Ren Chen, Xiao Chen, Yu-Ping Cai, Jian-Xin Lin, De-Ming Xu, Department of Anesthesiology, Affiliated Hospital of Putian College, Putian 351100, Fujian Province, China
Xiao-Chun Zheng, Department of Anesthesiology, Shenli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350001, Fujian Province, China
Author contributions: All authors contributed to the study conception and design; Zheng XC designed the study; Material preparation, data collection and analysis were performed by Lin XQ, Chen YR and Chen X; Cai YP, Lin JX and Xu DM contributed sample collection and intellectual input; The first draft of the manuscript was written by Lin XQ and all authors commented on previous versions of the manuscript; All authors read and approved the final manuscript; Lin XQ and Chen YR contributed equally to this study.
Supported byNatural Science Foundation of Fujian Province, No. 2019J01587.
Institutional review board statement: The present study was approved by the Ethics Committee of Putian College Affiliated Hospital, No. 201936.
Clinical trial registration statement: This study is registered at the Chinese Clinical trial registry, No. ChiCTR1900028529.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: The datasets generated during and/or analyzed during the current study are not publicly available but are available from the corresponding author on reasonable request.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Corresponding author: Xiao-Chun Zheng, MD, Professor, Department of Anesthesiology, Shenli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, No. 134 East Street, Fuzhou 350001, Fujian Province, China. zhengxiaochun2021@163.com
Received: December 22, 2021 Peer-review started: December 22, 2021 First decision: February 8, 2022 Revised: March 21, 2022 Accepted: April 21, 2022 Article in press: April 21, 2022 Published online: June 26, 2022 Processing time: 176 Days and 11.4 Hours
Core Tip
Core Tip: Enhanced recovery after surgery advocates that consuming carbohydrates two hours before anesthesia is beneficial to the patient's recovery. Patients with diabetes are prone to delayed gastric emptying. Different guidelines for preoperative carbohydrate consumption in patients with diabetes remain controversial due to concerns about the risk of regurgitation, aspiration and hyperglycemia. In this study, the preoperative carbohydrate load of type 2 diabetes (T2D) patients 2 h before anesthesia induction was found by ultrasonic gastric volume assessment and blood glucose monitoring. 200 mL does not increase the risk of reflux, aspiration, and hyperglycemia, but 300 mL glucose load may cause hyperglycemia in T2D patients before induction of anesthesia.
