Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10116
Peer-review started: July 6, 2021
First decision: July 26, 2021
Revised: August 8, 2021
Accepted: August 27, 2021
Article in press: August 27, 2021
Published online: November 26, 2021
Processing time: 139 Days and 1.2 Hours
The primary goal of antiepileptic treatments is to completely control epileptic seizures, while simultaneously considering prevention, control, and improvement of cognitive and behavioral dysfunction is of great significance for improving the patients’ intellectual development and quality of life.
In this study, the clinical and electroencephalograms (EEG) characteristics of children with benign epilepsy and centrotemporal spikes were analyzed, and the children’s treatment and outcomes also discussed.
This study aimed to determine the clinical and EEG characteristics and treatment results of benign epilepsy in spiking children.
A total of 106 benign epilepsy children with myocardial spines were included. Differences in clinical data and EGG characteristics between treatment-effective/-ineffective patients were analyzed, and children’s intellectual development before and after treatment evaluated using the Gesell Development Diagnostic Scale.
EEG showed that the discharge proportion in the awake and sleep periods was 66.04%, and the peak/peak discharge was mainly single-sided, accounting for 81.13%, while the discharge generalization accounted for 31.13%. The discharge index was negatively correlated with fine motor skill and language development, but not with the rest. The discharge index of the responsive group after treatment was significantly lower than that of the unresponsive group.
The EGG of children with benign epilepsy and centrotemporal spikes has characteristic changes, and therapeutic effects are affected by the age and attack frequency at the time of onset.
Further research expanding the sample size and extending follow-up time is needed.