Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10126
Peer-review started: May 28, 2021
First decision: July 1, 2021
Revised: July 3, 2021
Accepted: October 11, 2021
Article in press: October 11, 2021
Published online: November 26, 2021
Processing time: 177 Days and 19.9 Hours
A gastric glomus tumor is relatively rare, and there is little knowledge on its endoscopic ultrasound findings.
To assess the accuracy of endoscopic ultrasonography (EUS) in the diagnosis of gastric glomus tumor and to discuss its value by reviewing the literature.
A retrospective analysis of the EUS characteristics of gastric glomus tumor (such as tumor location, shape, size, echogenicity, homogeneity, margins, layer of origin, and so on) was performed. The study included 12 cases of gastric glomus tumor confirmed by surgery and pathology (7 females and 5 males, age range 36-74 years, average age was 58.2 years).
All the lesions were located in the gastric antrum (12 cases), protruding into the cavity, with a diameter between 1 and 3.5 cm. Glomus tumor of the stomach manifested as a circumscribed and slightly hypoechoic mass in the fourth layer, with an internal heterogeneous echo mixed with hyperechogenic spots and a marginal more hypoechoic halo. Smooth muscle actin, h-caldesmon and vimentin were shown to be positive by immunohistochemistry.
Although glomus tumor of the stomach is relatively rare, a typical glomus tumor of the stomach has characteristic changes under EUS.
Core Tip: Gastric glomus tumor is a rare non-epithelial benign vascular tumor and is difficult to diagnose with upper gastrointestinal endoscopy. We summarized the characteristics of endoscopic ultrasonography (EUS), computed tomography (CT) and pathology of 12 cases of gastric glomus tumor confirmed by pathology. The EUS characteristics of a gastric glomus tumor include a hypoechoic lesion originating from the fourth layer with a peripheral acoustic halo. Clinically, the diagnosis can be confirmed by the EUS characteristics combined with CT imaging findings.