Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2021; 9(32): 9970-9976
Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.9970
Computed tomography-guided chemical renal sympathetic nerve modulation in the treatment of resistant hypertension: A case report
Ge Luo, Jian-Jun Zhu, Ming Yao, Ke-Yue Xie
Ge Luo, Jian-Jun Zhu, Ming Yao, Ke-Yue Xie, Department of Anesthesiology and Pain, The Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China
Author contributions: All the authors have assessed the data and are responsible for the integrity and authenticity of the data; Luo G and Xie KY designed the experimental scheme; Zhu JJ was responsible for collating the original data; Luo G and Zhu JJ completed the draft of the manuscript and statistical analysis; Yao M and Xie KY provided technical support and approved the final manuscript.
Informed consent statement: The patient provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: All the authors have read the CARE Checklist (2016), and the manuscript was revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ke-Yue Xie, MD, Doctor, Department of Anesthesiology and Pain, The Affiliated Hospital of Jiaxing University, No. 1882 Zhong-Huan-South Road, Jiaxing 314000, Zhejiang Province, China. ballbe@163.com
Received: June 16, 2021
Peer-review started: June 16, 2021
First decision: July 26, 2021
Revised: July 26, 2021
Accepted: September 16, 2021
Article in press: September 16, 2021
Published online: November 16, 2021
Processing time: 146 Days and 13.2 Hours
Abstract
BACKGROUND

Resistant hypertension (RH) has always been a difficult problem in clinical diagnosis and treatment. At present, there is no recognized safe and effective minimally invasive treatment.

CASE SUMMARY

An 80-year-old woman was admitted to hospital due to trigeminal neuralgia (TN). The patient had a history of RH for more than 10 years and her blood pressure (BP) was not well-controlled. Before the treatment for TN, we decided to perform chemical renal sympathetic denervation with ethanol in the Pain Department of our hospital. One year after the operation, she stopped taking antihypertensive drugs, and her BP was satisfactorily controlled within 4 years after surgery.

CONCLUSION

Computed tomography-guided chemical renal sympathetic modulation may be a feasible method for the treatment of RH.

Keywords: Resistant hypertension; Renal sympathetic denervation; Ethanol; Case report

Core Tip: We report the use of computed tomography-guided renal sympathetic nerve modulation, for the first time, in the treatment of resistant hypertension in a patient with trigeminal neuralgia.