Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2021; 9(18): 4772-4777
Published online Jun 26, 2021. doi: 10.12998/wjcc.v9.i18.4772
Neonatal syringocystadenoma papilliferum: A case report
Hong-Jing Jiang, Zhao Zhang, Li Zhang, Yun-Jing Pu, Nian Zhou, Hong Shu
Hong-Jing Jiang, Zhao Zhang, Li Zhang, Yun-Jing Pu, Nian Zhou, Hong Shu, Department of Dermatology, Kunming Children's Hospital, Kunming 650034, Yunnan Province, China
Author contributions: Jiang HJ and Shu H carried out the studies, participated in collecting data, and drafted the manuscript; Zhang Z and Zhang L performed the statistical analysis and participated in its design; Pu YJ and Zhou N helped to draft the manuscript; All authors read and approved the final manuscript.
Informed consent statement: Consent was obtained from relatives of the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong Shu, MS, MSc, Department of Dermatology, Kunming Children's Hospital, No. 288 Qianxing Road, Kunming 650034, Yunnan Province, China. etyysh@gmail.com
Received: December 29, 2020
Peer-review started: December 29, 2020
First decision: March 27, 2021
Revised: April 8, 2021
Accepted: May 6, 2021
Article in press: May 6, 2021
Published online: June 26, 2021
Processing time: 163 Days and 21.1 Hours
Abstract
BACKGROUND

Syringocystadenoma papilliferum (SCAP) represents a rare, noncancerous adnexal tumor predominantly presenting at birth or in early childhood.

CASE SUMMARY

In this study, a 35-day-old girl was admitted to Kunming Children’s Hospital in October 2019 due to a lesion in the right frontotemporal region since birth. The surface of the lesion was bright red, granular, and papillary and easily bled upon touch, with about 1.5 cm × 4 cm in size. A subcutaneous mass was felt at the base of the lesion, with a size of about 3 cm × 5 cm. Dermatoscopy showed that the skin lesion was lobular and crumby. The lesion center was reddish or white, while the edges were white or yellowish band-like. There were polymorphic vascular structures and white radial streaks in the lesion, with some vascular clusters scattered. Pathological examination showed papilloma-like hyperplasia of the epidermis, with the epidermis partly sinking into the dermis to form several cystic depressions. Combining clinical and histopathological features, the child was diagnosed with SCAP. Follow-up is ongoing, and surgical resection will be performed.

CONCLUSION

This was a special clinical manifestation of SCAP, which complements the clinical manifestations of the disease and provides new insights for the diagnosis and differentiation of neonatal skin tumors.

Keywords: Syringocystadenoma papilliferum; Scalp; Newborn; Imaging; Histology; Case report

Core Tip: Syringocystadenoma papilliferum (SCAP) is a benign skin adnexal tumor whose origin and pathogenesis are unknown. The case reported here had a special clinical manifestation of SCAP. At birth, the skin lesion was bright red, papillary, and granulation-like, with a subcutaneous mass, surface exudation, and ease of bleeding upon touch, similar to the mature skin lesions of previous cases that had increased with age. The girl described in this report had a special clinical manifestation of SCAP, which complements the clinical manifestations of the disease and provides new insights for the diagnosis and differentiation of neonatal skin tumors.