Published online Apr 6, 2021. doi: 10.12998/wjcc.v9.i10.2302
Peer-review started: October 1, 2020
First decision: December 28, 2020
Revised: January 10, 2021
Accepted: January 25, 2021
Article in press: January 25, 2021
Published online: April 6, 2021
Processing time: 180 Days and 3.9 Hours
Chondrosarcoma, a cartilage matrix producing tumor, is the second most commonly observed primary bone tumor after osteosarcoma, accounting for 15% of all chest wall malignancies. We herein report the case of a patient with chondrosarcoma of the sternum and our management of the chest wall defects that presented following radical tumor resection.
A 31-year-old patient presented to our hospital with dull pain and a protruding mass overlying the chest for 3 mo. The presence of nocturnal pain and mass size progression was reported, as were overhead arm elevation-related limitations. Computed tomography showed a focal osteoblastic mass in the sternum with bony exostosis and adjacent soft tissue calcification. Positron emission tomography-computed tomography revealed hypermetabolic activity with a mass located over the upper sternum. Magnetic resonance imaging showed a focal ill-defined bony mass of the sternum with cortical destruction and periosteal reaction. Preoperative biopsy showed a consistent result with chondrosarcoma with immunohistochemical positivity for S100 and focal positivity for IDH-1. The grade II chondrosarcoma diagnosis was confirmed by postoperative pathology. The patient underwent radical tumor resection and chest wall reconstruction with a locking plate and cement spacer. The patient was discharged 1 wk after surgery without any complications. At the 1-year follow-up, there was no local recurrence on imaging. The functional scores, including Constant Score, Nottingham Clavicle Score, and Oxford Shoulder Score, showed the absence of pain in the performance of daily activities or substantial functional disabilities.
The diagnosis of chondrosarcoma must be considered when chest wall tumors are encountered. The surgical reconstructive materials, with a locking plate and cement spacer, used in our study are cost-effective and readily-available for the sternum defect.
Core Tip: Chondrosarcoma is the second most commonly observed primary bone tumor after osteosarcoma, accounting for 15% of all chest wall malignancies. Radical tumor excision is deemed the gold standard treatment. However, reconstruction of chest wall defect following tumor resection remains challenging. Our clinical case presents an innovative surgical procedure in managing chest wall defect. The surgical reconstructive materials including a locking plate and cement spacer are cost-effective and readily-available. We believe this technique, which yielded promising results, may serve as an alternative in cases such as ours.