Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2019; 7(17): 2580-2586
Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2580
Imaging of mixed epithelial and stromal tumor of the kidney: A case report and review of the literature
Jing Ye, Qing Xu, Jing Zheng, Shou-An Wang, Ya-Wei Wu, Jun-Hui Cai, Hu Yuan
Jing Ye, Qing Xu, Jing Zheng, Shou-An Wang, Ya-Wei Wu, Department of Medical Imaging, Clinic Medical School, Yangzhou University, Northern Jiangsu Province Hospital, Yangzhou 225000, Jiangsu Province, China
Jun-Hui Cai, Hu Yuan, Dalian Medical University, Dalian 116000, Liaoning Province, China
Author contributions: Ye J is the guarantor of integrity of the entire study; all authors contributed to approval of final version of submitted manuscript and agree to ensure that any questions related to the work are appropriately resolved; Zheng J contributed to clinical case studies; Wang SA, Cai JH, and Yuan H contributed to manuscript editing.
Supported by National Natural Science Foundation of China, No. 81401384; Social Develop Foundation of Yangzhou, No. 2017066;Yangzhou City Science and Education Strengthening Leading Talents Project, No. LJRC201810; Yangzhou City Science and Education Strengthening Key Talents Project, No. ZDRC201873.
Informed consent statement: Informed consent was obtained from the patient included in the study.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2013), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Qing Xu, MD, Doctor, Department of Medical Imaging, Clinic Medical School, Yangzhou University, Northern Jiangsu Province Hospital, No 98, Nantong West Road, Yangzhou 225000, Jiangsu Province, China. xuqing_yz@163.com
Telephone: +86-514-87373625
Received: March 12, 2019
Peer-review started: March 15, 2019
First decision: June 19, 2019
Revised: July 11, 2019
Accepted: July 27, 2019
Article in press: July 27, 2019
Published online: September 6, 2019
Processing time: 178 Days and 9.6 Hours
Abstract
BACKGROUND

Mixed epithelial and stromal tumors of the kidney (MESTKs) are a rare entity (about a hundred cases reported). They occur almost exclusively in postmenopausal women, with only seven cases reported in men. As this entity is very rare, little is known on its imaging features, especially magnetic resonance imaging (MRI) findings. In women, at MRI, the cystic component shows T1 hypointensity and T2 hyperintensity, while the solid component shows T1 hyperintensity and T2 hypointensity.

CASE SUMMARY

We report the computed tomography (CT) and MRI findings of MESTK in a 19-year-old male adolescent. To our knowledge, this case report is the first report of MRI findings of MESTK in male adolescents. The patient was admitted to Subei People's Hospital (Jiangsu Province, China) in July 2017 after a renal mass on the left side was detected by ultrasound during a clinical examination. Blood tests were all normal. Non-enhanced CT showed a round, well-circumscribed complex mass, approximately 45 mm × 40 mm in size. MRI revealed a clear well-circumscribed mass with a mixed arrangement of solid and cystic components. On T2 weighted images, some hypointensities were found in the solid areas. After contrast enhancement, moderate or mild enhancement was found in the solid component, which increased with time. A radical left nephrectomy was performed. The pathology analysis revealed a mixed epithelial and stromal tumor. The patient had no imaging findings of recurrence or metastasis at 12 months following surgery.

CONCLUSION

The possibility of MESTK should be considered in male adolescents. MRI can provide useful information for the preoperative diagnosis.

Keywords: Mixed epithelial and stromal tumor of the kidney; Adolescent; Magnetic resonance imaging; Preoperative diagnosis; Case report

Core tip: Mixed epithelial and stromal tumors of the kidney (MESTKs) are rare benign tumors that occur predominantly in women. Little is known on its imaging features, especially magnetic resonance imaging (MRI) findings. We report the computed tomography and MRI findings of MESTK in a 19-year-old male adolescent. To our knowledge, this is the first report of MRI findings of MESTK in male adolescents. Although it occurs predominantly in menopausal women, the possibility of MESTK should be considered in male adolescents with a cystic solid mass in the kidney. MRI can provide useful information for the preoperative diagnosis.