Nurani KM, Natalia G, Kadernani N, Kadernani K. Systemic and dermatological findings of immunoglobulin A vasculitis in a black child: A case report. World J Clin Cases 2025; 13(35): 115280 [DOI: 10.12998/wjcc.v13.i35.115280]
Corresponding Author of This Article
Najib Kadernani, MD, School of Medicine, University of Nairobi, Hospital Road, Upper Hill, Nairobi, Kenya, Nairobi 30197-00100, Nairobi City, Kenya. najib.ayub14@gmail.com
Research Domain of This Article
Dermatology
Article-Type of This Article
Case Report
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dec 16, 2025 (publication date) through Dec 16, 2025
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Journal Information of This Article
Publication Name
World Journal of Clinical Cases
ISSN
2307-8960
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Nurani KM, Natalia G, Kadernani N, Kadernani K. Systemic and dermatological findings of immunoglobulin A vasculitis in a black child: A case report. World J Clin Cases 2025; 13(35): 115280 [DOI: 10.12998/wjcc.v13.i35.115280]
Khulud Mahmood Nurani, Gloria Natalia, Najib Kadernani, School of Medicine, University of Nairobi, Nairobi 30197-00100, Nairobi City, Kenya
Khalid Kadernani, Department of Medicine, Nairobi West Hospital, Nairobi 19676 - 00100, Nairobi City, Kenya
Author contributions: Nurani K and Kadernani N took patient history; Nurani K, Kadernani K, and Natalia G drafted the case report.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Najib Kadernani, MD, School of Medicine, University of Nairobi, Hospital Road, Upper Hill, Nairobi, Kenya, Nairobi 30197-00100, Nairobi City, Kenya. najib.ayub14@gmail.com
Received: October 15, 2025 Revised: November 5, 2025 Accepted: December 8, 2025 Published online: December 16, 2025 Processing time: 64 Days and 14.2 Hours
Abstract
BACKGROUND
Immunoglobulin A (IgA) vasculitis, formerly known as Henoch-Schönlein purpura, is a small vessel vasculitis predominantly affecting children. It commonly presents with a triad of purpuric rash, arthralgia, and abdominal pain. However, dermatologic manifestations of IgA vasculitis in black-skinned individuals are poorly documented in literature.
CASE SUMMARY
This case report describes an 11-year-old black girl with acute onset of rash, joint pain, and abdominal pain, subsequently diagnosed with IgA vasculitis.
CONCLUSION
The case highlights the importance of early recognition and supportive management in ensuring a favorable outcome, particularly in dark-skinned populations.
Core Tip: Immunoglobulin A (IgA) vasculitis, rare in black children, can be missed when classic purpura is subtle on dark skin. Early triad recognition—palpable rash, arthralgia, abdominal pain—and prompt supportive care secure rapid recovery. This case describes an 11-year-old Black girl with classic systemic features—palpable purpura, abdominal pain, and arthritis—but with atypical dermatologic presentation due to skin pigmentation. The report underscores the diagnostic challenges of identifying vasculitic rashes in darker skin and highlights the need for inclusive dermatologic education and region-specific research on IgA vasculitis presentation and outcomes in African children.
