Liu H, Ke F, Li CZ, Li SP, He XQ, Lu H. Clinical application of radiofrequency technology in the treatment of facial skin wrinkles and laxity. World J Clin Cases 2025; 13(25): 97335 [DOI: 10.12998/wjcc.v13.i25.97335]
Corresponding Author of This Article
Hua Lu, MD, Chief Physician, Department of Medical Cosmetology, Renmin Hospital, Hubei University of Medicine, No. 238 Jiefang Road, No. 99 ZhangZhidong Road, Wuchang District, Shiyan 442000, Hubei Province, China. luhuang8210@163.com
Research Domain of This Article
Dermatology
Article-Type of This Article
Clinical Trials Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Hua Liu, Fei Ke, Cheng-Zhi Li, Shu-Ping Li, Xue-Qin He, Hua Lu, Department of Medical Cosmetology, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei Province, China
Author contributions: Liu H and Ke F designed the research study; Li CZ and Li SP performed the research; He XQ and Lu H conducted experiments, analyzed the data; and all authors contributed to editorial changes in the manuscript, read and approved the final manuscript.
Institutional review board statement: This study was approved by the ethics committee of Renmin Hospital, Hubei University of Medicine.
Clinical trial registration statement: This study is not registered.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement:sharing statement: The datasets used and analysed during the current study are available from the corresponding author on reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hua Lu, MD, Chief Physician, Department of Medical Cosmetology, Renmin Hospital, Hubei University of Medicine, No. 238 Jiefang Road, No. 99 ZhangZhidong Road, Wuchang District, Shiyan 442000, Hubei Province, China. luhuang8210@163.com
Received: May 28, 2024 Revised: October 30, 2024 Accepted: May 21, 2025 Published online: September 6, 2025 Processing time: 404 Days and 22.1 Hours
Abstract
BACKGROUND
Aging is an inevitable aspect of human life, characterized by the gradual decline in the function of individual cells and structural components, including bones, muscles, and ligaments.
AIM
To evaluate the clinical effects of radiofrequency technology in treating facial skin wrinkles and laxity.
METHODS
This study included 60 female patients, aged 36-58 years (mean age 47.71 ± 1.56 years), who received focused radiofrequency technology treatment for facial wrinkles and laxity in the Department of Medical Cosmetology at our hospital between January 2021 and June 2022. Each patient underwent three treatment sessions, one every two months. Facial photographs were taken before treatment and one week after the final session. A single physician assessed wrinkle severity using a standardized wrinkle severity scale, and patients completed a satisfaction questionnaire one week after the last treatment.
RESULTS
After three consecutive radiofrequency treatments, performed every two months, patients exhibited significantly reduced wrinkles and skin laxity compared to baseline. One week after the third treatment, the mean facial wrinkle severity score had significantly decreased from 3.00 ± 0.79 to 2.71 ± 0.47 (t = 2.58, P < 0.05). Additionally, 88.24% of patients reported noticeable improvements in facial wrinkles and skin laxity. No serious adverse reactions occurred during or following treatment.
CONCLUSION
Radiofrequency technology demonstrates significant clinical efficacy in improving facial skin wrinkles and laxity.
Core Tip: Radiofrequency technology has a remarkable clinical effect on the improvement of facial skin wrinkles and relaxation. To assess clinical efficacy of radiofrequency for facial wrinkles/laxity, 60 female patients received three focused radiofrequency treatments for facial aging at a medical cosmetology department. Post-treatment, the mean facial wrinkle severity score decreased significantly. 88.24% of patients reported noticeable improvements. No serious adverse events occurred.
