Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2024; 12(1): 163-168
Published online Jan 6, 2024. doi: 10.12998/wjcc.v12.i1.163
Endophthalmitis in silicone oil-filled eye: A case report
Hui-Chao Yan, Ze-Lu Wang, Wen-Zhen Yu, Ming-Wei Zhao, Jian-Hong Liang, Hong Yin, Xuan Shi, Heng Miao
Hui-Chao Yan, Ze-Lu Wang, Wen-Zhen Yu, Ming-Wei Zhao, Jian-Hong Liang, Hong Yin, Xuan Shi, Heng Miao, Department of Ophthalmology, Peking University People’s Hospital, Beijing 100044, China
Author contributions: Yan HC wrote the paper; Wang ZL polished the paper; Yu WZ designed the research; Zhao MW, Liang JH, Yin H, Shi X, and Miao H provided the information of the case.
Supported by National Key R and D Program of China, No. 2020YFC2008200.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen-Zhen Yu, MD, Professor, Department of Ophthalmology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing 100044, China. wenzhen_yu@sina.com
Received: September 9, 2023
Peer-review started: September 9, 2023
First decision: November 16, 2023
Revised: November 27, 2023
Accepted: December 5, 2023
Article in press: December 5, 2023
Published online: January 6, 2024
Processing time: 114 Days and 22.6 Hours
Abstract
BACKGROUND

Endophthalmitis occurring in silicone oil-filled eyes is a very rare occurrence, with reported incidence rates ranging between 0.07% and 0.039%. Traditional methods of management of infectious endophthalmitis include the removal of silicone oil, washout of the vitreous cavity, administration of intravitreal antibiotics, and re-injection of silicone oil.

CASE SUMMARY

Herein, we report the case of a 39-year-old man with unilateral endophthalmitis after pars plana vitrectomy and silicone oil tamponade. Intravitreal injections of full-dose antibiotics and anterior chamber washout were used to treat the patient. No signs of retinal toxicity were observed during the follow-up period.

CONCLUSION

Intravitreal full-dose antibiotic injections and anterior chamber washout are promising alternatives to traditional therapies for endophthalmitis in silicone oil-filled eyes.

Keywords: Endophthalmitis; Intravitreal injection; Silicone oil-filled eye; Pars plana vitrectomy; Washout; Case report

Core Tip: Endophthalmitis in silicone oil-filled eyes occurs very rarely. Traditional methods of management of infectious endophthalmitis include removal of the silicone oil, washout of the vitreous cavity, administration of intravitreal antibiotics, and re-injection of silicone oil. Here, we report the case of a 39-year-old man with unilateral endophthalmitis following vitrectomy and silicone oil tamponade surgery. The patient underwent two anterior chamber washouts and received three intravitreal antibiotic injections, resulting in successful control of the endophthalmitis.