Di QY, Long XD, Ning J, Chen ZH, Mao ZQ. Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature. World J Clin Cases 2023; 11(3): 662-668 [PMID: 36793644 DOI: 10.12998/wjcc.v11.i3.662]
Corresponding Author of This Article
Xiang-Dang Long, PhD, Professor, Department of Ultrasound, The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People’s Hospital, No. 61 of Jiefang West Road, Changsha 410005, Hunan Province, China. 376262716@qq.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 26, 2023; 11(3): 662-668 Published online Jan 26, 2023. doi: 10.12998/wjcc.v11.i3.662
Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature
Qiu-Yi Di, Xiang-Dang Long, Jing Ning, Zhi-Hong Chen, Zhi-Qun Mao
Qiu-Yi Di, Xiang-Dang Long, Jing Ning, Department of Ultrasound, The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People’s Hospital, Changsha 410005, Hunan Province, China
Zhi-Hong Chen, Department of Pathology, The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People’s Hospital, Changsha 410005, Hunan Province, China
Zhi-Qun Mao, Department of Radiology, The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People’s Hospital, Changsha 410005, Hunan Province, China
Author contributions: Di QY performed the manuscript writing and the literature collecting; Cheng ZH and Mao ZQ were involved in the operation; Di QY, Ning J and Long XD conceived, designed, and supervised all studies and the drafting and editing of the manuscript; and all the authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiang-Dang Long, PhD, Professor, Department of Ultrasound, The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People’s Hospital, No. 61 of Jiefang West Road, Changsha 410005, Hunan Province, China. 376262716@qq.com
Received: October 31, 2022 Peer-review started: October 31, 2022 First decision: November 14, 2022 Revised: December 1, 2022 Accepted: January 5, 2023 Article in press: January 5, 2023 Published online: January 26, 2023 Processing time: 87 Days and 5 Hours
Abstract
BACKGROUND
Extraskeletal osteosarcoma (ESOS) is a highly malignant osteosarcoma that occurs in extraskeletal tissues. It often affects the soft tissues of the limbs. ESOS is classified as primary or secondary. Here, we report a case of primary hepatic osteosarcoma in a 76-year-old male patient, which is very rare.
CASE SUMMARY
Here, we report a case of primary hepatic osteosarcoma in a 76-year-old male patient. The patient had a giant cystic-solid mass in the right hepatic lobe that was evident on ultrasound and computed tomography. Postoperative pathology and immunohistochemistry of the mass, which was surgically removed, suggested fibroblastic osteosarcoma. Hepatic osteosarcoma reoccurred 48 d after surgery, resulting in significant compression and narrowing of the hepatic segment of the inferior vena cava. Consequently, the patient underwent stent implantation in the inferior vena cava and transcatheter arterial chemoembolization. Unfortunately, the patient died of multiple organ failure postoperatively.
CONCLUSION
ESOS is a rare mesenchymal tumor with a short course and a high likelihood of metastasis and recurrence. The combination of surgical resection and chemotherapy may be the best treatment.
Core Tip: Hepatic osteosarcoma is a rare mesenchymal tumor with a short duration and a high likelihood of metastasis and recurrence. Although the imaging examination can help detect lesions, it is difficult to distinguish from other lesions with multiple osteosarcoma-like lesions and make accurate preoperative diagnosis. If hepatic osteosarcoma is suspected, a biopsy and surgery should be performed as soon as possible.
