Progress and expectation of stem cell therapy for diabetic wound healing

doi:10.12998/wjcc.v11.i3.506

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 11, Issue 3

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (5901)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-1) series.

Item

Count

PDF

248

WORD

HTML

3451

Tables (1-1)

634

Sum=4366

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

336

Download

1211

Sum=1547

Jan 26, 2023 (publication date) through Feb 26, 2026

Times Cited of This Article

Times Cited (12)

Journal Information of This Article

Publication Name

World Journal of Clinical Cases

ISSN

2307-8960

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Minireviews

World J Clin Cases. Jan 26, 2023; 11(3): 506-513
Published online Jan 26, 2023. doi: 10.12998/wjcc.v11.i3.506

Progress and expectation of stem cell therapy for diabetic wound healing

Zhen-Han Xu, Meng-Hui Ma, Yan-Qing Li, Li-Lin Li, Gui-Hua Liu

Zhen-Han Xu, Meng-Hui Ma, Yan-Qing Li, Li-Lin Li, Gui-Hua Liu, Reproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510610, Guangdong Province, China

Author contributions: Xu ZH, Ma MH, Li YQ, Li LL and Liu GH designed the research study; Xu ZH, Ma MH, Li YQ and Li LL performed the research; Xu ZH and Ma MH contributed literature search; Xu ZH, Li LL and Liu GH contributed data analysis; Xu ZH and Li YQ wrote the manuscript; All authors have read and approve the final manuscript.

Supported by The National Natural Science Foundation of China, No. 82171604.

Conflict-of-interest statement: All the authors declare that there are no conflicts of interest associated with this manuscript.

Corresponding author: Gui-Hua Liu, MD, PhD, Associate Chief Physician, Associate Research Scientist, Reproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Yuancuner Road, Tianhe District, Guangzhou 510610, Guangdong Province, China. liuguihua@mail.sysu.edu.cn

Received: August 31, 2022
Peer-review started: August 31, 2022
First decision: September 26, 2022
Revised: November 8, 2022
Accepted: January 9, 2023
Article in press: January 9, 2023
Published online: January 26, 2023
Processing time: 148 Days and 3.1 Hours

Abstract

Impaired wound healing presents great health risks to diabetics. Encouragingly, the current clinical successfully found out meaningful method to repair wound tissue, and stem cell therapy could be an effective method for diabetic wound healing with its ability to accelerate wound closure and avoid amputation. This minireview aims at introducing stem cell therapy for facilitating tissue repair in diabetic wounds, discussing the possible therapeutic mechanism and clinical application status and problems.

Keywords: Stem cell; Diabetic wound; Wound healing; Immunoregulation

Core Tip: Diabetic wound is a common complication of diabetes and stem cell therapy is an effective treatment for diabetic wounds. It helps improve wounds mainly by regulating inflammation and blood circulation. At present, many kinds of stem cells have been used and studied, and good results have been achieved. However, there are still problems that need to be solved. Here we discuss the current role and progress of stem cells in the treatment of diabetic wounds.