Published online Sep 26, 2023. doi: 10.12998/wjcc.v11.i27.6565
Peer-review started: June 6, 2023
First decision: August 4, 2023
Revised: August 11, 2023
Accepted: August 25, 2023
Article in press: August 25, 2023
Published online: September 26, 2023
Processing time: 103 Days and 7.7 Hours
With the withdrawal of paraquat from the market, diquat is widely used, so the treatment of diquat poisoning has become one of the focuses of emergency poisoning diagnosis and treatment.
We studied the case of a 17-year-old male patient who drank 200 mL (20 g/100 mL) of diquat solution two hours before arriving at the hospital. Despite the use of treatments such as gastric lavage, hemoperfusion, continuous hemodialysis, glucocorticoids, and organ support, the patient’s condition rapidly progressed to multiorgan failure, and he died 23.5 h after admission.
We summarized the clinical characteristics and treatment strategies of diquat poisoning through this case and performed a literature review to provide a basis and direction for clinical treatment.
Core Tip: The clinical manifestations of diquat poisoning are mainly local mucosal injury and multiple organ damage. The earlier organ function damage occurs, and the more systems are involved, the poorer the prognosis is. In addition, the prognosis of patients is significantly correlated with the poisoning dose, and fulminant poisoning has a high mortality rate. In the treatment of patients, early and adequate removal of toxins is the focus of treatment, and comprehensive and systematic organ function evaluation and support is also an important part of treatment.