Liu ZH, Li GD, Hao QX, Cao F, Cheng Y, Kou MJ, Jiao Y. Acute exacerbation of idiopathic pulmonary fibrosis treated using the Feibi recipe: Two case reports. World J Clin Cases 2023; 11(24): 5742-5748 [PMID: 37727712 DOI: 10.12998/wjcc.v11.i24.5742]
Corresponding Author of This Article
Yang Jiao, MD, Professor, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, No. 6 Fang Zhuang Fang Xing Yuan, Fengtai District, Beijing 100078, China. yangjiao2013@sina.cn
Research Domain of This Article
Respiratory System
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Zhao-Heng Liu, School of Life Sciences, Beijing University of Chinese Medicine, Beijing 102488, China
Guo-Dong Li, Department of Respiratory, Beijing Changping Hospital of Integrated Traditional Chinese and Western Medicine, Beijing 102208, China
Qing-Xun Hao, Fang Cao, Yu Cheng, Meng-Jia Kou, Yang Jiao, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100078, China
Author contributions: Liu ZH and Li GD contribute equally to this work; Liu ZH wrote the paper; Li GD designed the report; Hao QX and Cao F collected the patients’ clinical data and took pictures; Cheng Y and Kou MJ followed up the patients; Jiao Y treated the patients and support the research.
Supported byBeijing Natural Science Foundation, No. 7202118; National Natural Science Foundation of China, No. 81573970; and Basic Scientific Research Foundation of Beijing University of Chinese Medicine, No. 2021-JYB-XJSJJ-033.
Informed consent statement: Written informed consent for publication of medical information was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yang Jiao, MD, Professor, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, No. 6 Fang Zhuang Fang Xing Yuan, Fengtai District, Beijing 100078, China. yangjiao2013@sina.cn
Received: April 16, 2023 Peer-review started: April 16, 2023 First decision: May 19, 2023 Revised: June 25, 2023 Accepted: July 31, 2023 Article in press: July 31, 2023 Published online: August 26, 2023 Processing time: 130 Days and 22.7 Hours
Abstract
BACKGROUND
Rationale: No other treatment besides lung transplant is effective for idiopathic pulmonary fibrosis (IPF). Patients with IPF have poor prognosis, which may eventually lead to death. Patient concerns: Two female patients were diagnosed with IPF. In our recent follow-up, both these patients maintained a good quality of life.
CASE SUMMARY
Diagnosis: Both patients had dry cough and progressive dyspnea. Interventions: The first patient was treated with prednisone, and the second patient was treated with prednisone and tripterygium glycosides. However, the symptoms did not improve and fibrosis was not controlled. Thus, the Feibi recipe was used. Outcomes: No deterioration was observed after the treatment, and the dry cough and its effect were ameliorated. Furthermore, they are still alive and the quality of their lives has improved.
CONCLUSION
These two cases suggest that the Feibi recipe and other traditional Chinese medicine therapies could be beneficial for IPF treatment.
Core Tip: In this report, we present the cases of two patients diagnosed with idiopathic pulmonary fibrosis with progressive fibrosing who received traditional Chinese medicine (TCM). The disease progression slowed down, and the symptoms were relieved. After several years of follow-up, we collected their medical history, computed tomography scans, and found that the patients had a moderate quality of life after the TCM treatment.
