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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Dec 25, 2025; 14(4): 114174
Published online Dec 25, 2025. doi: 10.5501/wjv.v14.i4.114174
Published online Dec 25, 2025. doi: 10.5501/wjv.v14.i4.114174
Atypical presentation of pediatric acute hepatitis A: Is the situation alarming?
Rubaiyat Alam, Department of Pediatric Gastroenterology and Nutrition, Bangladesh Medical University, Dhaka 1000, Bangladesh
Author contributions: Alam R solely contributed to the conception, literature review, drafting, and revision of the manuscript, approved the final version, and is responsible for the integrity of the entire work.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rubaiyat Alam, Assistant Professor, Department of Pediatric Gastro
Received: September 15, 2025
Revised: November 6, 2025
Accepted: December 3, 2025
Published online: December 25, 2025
Processing time: 103 Days and 21.1 Hours
Revised: November 6, 2025
Accepted: December 3, 2025
Published online: December 25, 2025
Processing time: 103 Days and 21.1 Hours
Core Tip
Core Tip: Although pediatric hepatitis A is usually self-limiting, atypical presentations, such as cholestatic, relapsing, and autoimmune-triggered forms, can prolong morbidity and, occasionally, be life-threatening. This mini-review summarizes the clinical spec