Real-life practice of Kelleni’s protocol in treatment and post exposure prophylaxis of SARS-CoV-2 HV.1 and JN.1 subvariants

doi:10.5501/wjv.v14.i3.107903

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Sep 25, 2025 (publication date) through Feb 17, 2026

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Virol. Sep 25, 2025; 14(3): 107903
Published online Sep 25, 2025. doi: 10.5501/wjv.v14.i3.107903

Real-life practice of Kelleni’s protocol in treatment and post exposure prophylaxis of SARS-CoV-2 HV.1 and JN.1 subvariants

Mina Thabet Kelleni

Mina Thabet Kelleni, Department of Pharmacology, College of Medicine, Minia University, Minya 61519, Egypt

Author contributions: Kelleni MT is responsible for all aspects of the writing and publication process of the manuscripts.

Conflict-of-interest statement: Dr. Kelleni has nothing to disclose.

Corresponding author: Mina Thabet Kelleni, MD, PhD, Assistant Professor, Department of Pharmacology, College of Medicine, Minia University, Main Road Shalaby Land, Minya 61519, Egypt. mina.kelleni@mu.edu.eg

Received: April 2, 2025
Revised: May 17, 2025
Accepted: July 24, 2025
Published online: September 25, 2025
Processing time: 178 Days and 19.1 Hours

Core Tip

Core Tip: Coronavirus disease 2019 (COVID-19) has claimed the lives of over seven million people worldwide. Most deaths have occurred among high-risk patients, making it crucial to find a protocol that is effective for post-exposure prophylaxis in this pandemic and future ones. This article provides insight into how Kelleni’s protocol was successfully and safely used to save lives among high-risk groups of COVID-19 patients amidst the ongoing evolution of severe acute respiratory syndrome coronavirus 2.