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World J Psychiatry. May 19, 2026; 16(5): 116272
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.116272
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.116272
Incidence and risk factors of post-traumatic stress disorder in patients after endoscopic submucosal dissection for early gastric cancer
Jin Liu, Department of Endoscopy Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Yong Wang, Medical Device Registration Review Section, Chongqing Center for Drug Evaluation and Inspection, Chongqing 401120, China
Rong-Hua Wang, Office of Academic Affairs, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Author contributions: Liu J and Wang RH conceived and designed the study; Liu J collected and analyzed the data and wrote the initial draft; Wang Y contributed to data analysis and methodology; Wang RH supervised the study and critically revised the manuscript. All authors approved the final version for submission.
Institutional review board statement: This study was reviewed and approved by the Medical Research Ethics Review Committee of The First Affiliated Hospital of Chongqing Medical University (No. 2024-589-01).
Informed consent statement: Informed consent was waived by the Medical Research Ethics Review Committee of The First Affiliated Hospital of Chongqing Medical University because this was a retrospective observational study using de-identified clinical data with no direct patient contact.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets generated and analyzed during the current study are available from the corresponding author upon reasonable request.
Corresponding author: Rong-Hua Wang, Office of Academic Affairs, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. ronghua6662025@163.com
Received: November 18, 2025
Revised: January 1, 2026
Accepted: February 6, 2026
Published online: May 19, 2026
Processing time: 162 Days and 23 Hours
Revised: January 1, 2026
Accepted: February 6, 2026
Published online: May 19, 2026
Processing time: 162 Days and 23 Hours
Core Tip
Core Tip: We quantified post-traumatic stress disorder 3 months after endoscopic submucosal dissection for early gastric cancer and identified six independent preoperative factors - age, marital status, lesion size, ulcer, depression level, and social support. A pragmatic 6-factor model showed good discrimination (area under the curve = 0.856) and allows risk stratification before treatment. This approach supports routine preoperative screening and targeted psychological intervention to improve adherence and recovery.