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World J Psychiatry. Apr 19, 2026; 16(4): 116632
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.116632
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.116632
Correlation of anxiety and depression with sleep quality and post-traumatic growth in brain tumor patients and associated determinants
Ya-Zhi Deng, School of Medicine, Hunan Normal University, Changsha 410013, Hunan Province, China
Juan Sun, Department of Intensive Care Medicine, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Man Zhang, Department of Geriatrics, Graduate School of Qinghai University, Xining 810000, Qinghai Province, China
Xiao-Bo Zhang, Department of Neurology, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Min Yuan, Department of Neurosurgery, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Yu-Fei Li, Department of Surgery, Department of Clinical Medicine, School of Medicine, Hunan Normal University, Changsha 410013, Hunan Province, China
Co-corresponding authors: Min Yuan and Yu-Fei Li.
Author contributions: Deng YZ contributed to the manuscript writing, data collection and analysis; Deng YZ, Sun J, Zhang M, and Zhang XB collected data; Yuan M and Li YF were involved in the conceptualization and supervision of this manuscript, they contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the First People’s Hospital of Changde City, No. YX-2023-078-01.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No additional data are available.
Corresponding author: Yu-Fei Li, PhD, Department of Surgery, Department of Clinical Medicine, School of Medicine, Hunan Normal University, No. 371 Tongzipo Road, Changsha 410013, Hunan Province, China. lyflyf6662025@163.com
Received: December 9, 2025
Revised: January 12, 2026
Accepted: March 4, 2026
Published online: April 19, 2026
Processing time: 110 Days and 23.3 Hours
Revised: January 12, 2026
Accepted: March 4, 2026
Published online: April 19, 2026
Processing time: 110 Days and 23.3 Hours
Core Tip
Core Tip: This study reports the correlations between anxiety, depression, sleep quality, and post-traumatic growth (PTG) in patients with brain tumors (BTs) and identifies related influencing factors. The findings indicate that patients with BT commonly experience negative emotions such as anxiety and depression, accompanied by relatively severe sleep disorders and insufficient PTG. These negative emotional states are strongly associated with sleep quality and PTG. Factors, including age < 50 years, educational level below high school, PTG-inventory score < 60, and Pittsburgh Sleep Quality Index score ≥ 11, increases the likelihood of anxiety or depression in patients with BTs.