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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. Apr 19, 2026; 16(4): 115951
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115951
Letter to the Editor: Interplay between ocular surface function, sleep quality, and psychological factors in dry eye disease
Arvind Kumar Morya, Rannusha Morya, Srishti Khullar
Arvind Kumar Morya, Department of Ophthalmology, All India Institute of Medical Sciences, Hyderabad 508126, Telangana, India
Rannusha Morya, Department of Psychology, Manipal University, Jaipur 303007, Rajasthan, India
Srishti Khullar, Department of Ophthalmology, Military Hospital, Agra 282001, Uttar Pradesh, India
Author contributions: Morya AK drafted the manuscript; Morya AK and Morya R conceived and designed the study; Morya R and Khullar S performed the literature review and critical revision; all authors approved the final version of the manuscript.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Corresponding author: Arvind Kumar Morya, Additional Professor, Department of Ophthalmology, All India Institute of Medical Sciences, Bibi Nagar, Hyderabad 508126, Telangana, India. bulbul.morya@gmail.com
Received: October 30, 2025
Revised: November 12, 2025
Accepted: December 25, 2025
Published online: April 19, 2026
Processing time: 152 Days and 2.2 Hours
Core Tip

Core Tip: Dry eye disease (DED) is not merely a localized ocular disorder but part of a wider systemic and psychological network. Sleep disturbance, anxiety, and depression can exacerbate DED symptoms, while chronic ocular discomfort itself may precipitate poor sleep and mood changes. Risk is higher in pregnant individuals, people with diabetes, patients taking certain medications, and those over 45 years. Depression showed a strong link to increased corneal staining, while both age and sleep disturbances predicted symptom exacerbation. Increased screen time contributes to digital eye strain and incomplete blinking, further destabilizing the tear film. Clinicians should incorporate mental health and sleep screening into DED management to improve both ocular and systemic quality of life.