Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. Apr 19, 2026; 16(4): 115468
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115468
Published online Apr 19, 2026. doi: 10.5498/wjp.v16.i4.115468
Risk factors associated with anxiety and depression in patients with inflammatory bowel disease identified using structural equation modeling
Yan Zeng, Department of Gastroenterology, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Xue Yang, Department of General Practice, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Xiao-Bo Zhang, Department of Neurology, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Yan Liu, Department of Psychiatry, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Juan Sun, Department of Intensive Care Medicine, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415003, Hunan Province, China
Author contributions: Zeng Y wrote and critically revised the manuscript; Yang X performed the experiments, collected and analyzed the data; Zhang XB and Liu Y provided essential technical support; Sun J designed and supervised the study. All authors approval the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City) (Approval No. 2025-392-01).
Informed consent statement: All study participants or their legal guardians provided written informed consent before study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Data supporting the findings of this study are available from the corresponding author upon request.
Corresponding author: Juan Sun, Department of Intensive Care Medicine, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), No. 388 Renmin East Road, Changde 415003, Hunan Province, China.
Received: October 31, 2025
Revised: December 8, 2025
Accepted: January 8, 2026
Published online: April 19, 2026
Processing time: 150 Days and 0.7 Hours
Revised: December 8, 2025
Accepted: January 8, 2026
Published online: April 19, 2026
Processing time: 150 Days and 0.7 Hours
Core Tip
Core Tip: This study applies structural equation modeling to explore factors influencing anxiety and depression in patients with inflammatory bowel disease. It identifies sleep quality and coping modes as key factors influencing anxiety and depression in patients with inflammatory bowel disease. These findings highlight the need for tailored interventions like sleep hygiene education and cognitive-behavioral strategies, could significantly alleviate anxiety and depression, thereby improving overall mental health outcomes and quality of life in this patient population.