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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jan 19, 2026; 16(1): 109403
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.109403
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.109403
Association between anxiety, depression, and fatigue in elderly patients with Parkinson’s disease
Meng-Na Yang, Xiao-Yu Peng, Department of Neurorehabilitation, The Second Rehabilitation Hospital of Shanghai, Shanghai 200431, China
Ye-Ping Chen, Department of Science and Education, The Second Rehabilitation Hospital of Shanghai, Shanghai 200431, China
Author contributions: Yang MN wrote a manuscript, provided administrative support, collected and assembled the data, performed data analysis and interpretation; Yang MN and Peng XY provided the study materials; Yang MN and Chen YP conceptualized and designed the study; all authors participated in manuscript writing and approved the final manuscript.
Supported by Foundation of Shanghai Baoshan Science and Technology Commission, No. 2024-E-66; and Shanghai Nursing Association Scientific Research Project, No. 2024MS-B02.
Institutional review board statement: This study was approved by the Ethic Committee of The Second Rehabilitation Hospital of Shanghai.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: We have no financial relationships to disclose.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ye-Ping Chen, Associate Chief Nurse, Department of Science and Education, The Second Rehabilitation Hospital of Shanghai, No. 8 Lane 860, Changjiang Road, Baoshan District, Shanghai 200431, China. chenyeping1981@163.com
Received: August 15, 2025
Revised: September 26, 2025
Accepted: November 6, 2025
Published online: January 19, 2026
Processing time: 137 Days and 19 Hours
Revised: September 26, 2025
Accepted: November 6, 2025
Published online: January 19, 2026
Processing time: 137 Days and 19 Hours
Core Tip
Core Tip: Parkinson’s disease (PD) predominantly affects middle-aged and elderly individuals, with an increasing incidence in aging populations. Anxiety and depression are major psychological symptoms that intensify caregiver dependence and impose heavy burdens on patients and families. Fatigue, another disabling but underrecognized non-motor symptom, further compounds disease impact. However, few studies have addressed its relationship with anxiety and depression in PD. This study assessed the prevalence of anxiety and depression, identified related factors, and analyzed their correlation with fatigue severity.