Published online Oct 19, 2025. doi: 10.5498/wjp.v15.i10.106312
Revised: April 21, 2025
Accepted: August 7, 2025
Published online: October 19, 2025
Processing time: 188 Days and 23.7 Hours
Atopic dermatitis is a chronic inflammatory skin disease that poses a substantial burden on patients' physical health, as well as on their psychological health and quality of life. This study specifically examines active disease phases (excluding spontaneous remission periods) to investigate the efficacy of continuous treat
To evaluate the effectiveness of continuous treatment strategies, including der
A retrospective cohort study was conducted on 120 atopic dermatitis patients treated at our hospital between June 2023 and May 2024. A total of 120 patients were randomly assigned into control and intervention groups (60 patients each). The control group underwent routine treatment, and the intervention group was treated using continuous treatment strategies, including personalized skin care plan, psychological counseling, patient education, and long-term follow-up. Quality of life and psychological status of patients were assessed using the dermatology life quality index and Hospital Anxiety and Depression Scale.
At 12 months post-intervention, the dermatology life quality index scores in the intervention group were significantly lower than those in the control group (P < 0.01), implying improved quality of life. The anxiety and depression symptoms were significantly lower in the intervention group when compared to the control group (P < 0.05) as per the Hospital Anxiety and Depression Scale. In the intervention group, the rate of recurrence of skin symptoms was 15% compared to 35% in the control group, with a statistically significant difference between the two groups.
Continuous treatment for atopic dermatitis patients greatly improve their psychological state and quality of life, enhance disease-free survival, and offer new trains of thought for clinical treatment. Personalized integrated management over a prolonged time is important to improve quality of life in such patients.
Core Tip: This retrospective study demonstrates that continuous integrated treatment, including dermatological care, psychological counseling, patient education, and structured follow-up, significantly improves mental health and quality of life in patients with atopic dermatitis. Compared to routine care, the intervention group showed marked reductions in anxiety, depression, perceived stress, and sleep disturbances, along with improved treatment adherence and social functioning. These findings support a paradigm shift toward multidisciplinary, long-term management of atopic dermatitis that addresses both dermatological and psychological needs.