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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Jul 24, 2025; 16(7): 107781
Published online Jul 24, 2025. doi: 10.5306/wjco.v16.i7.107781
Published online Jul 24, 2025. doi: 10.5306/wjco.v16.i7.107781
Early detection of gallbladder cancer: Current status and future perspectives
Yajnadatta Sarangi, Ashok Kumar, Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, Uttar Pradesh, India
Co-first authors: Yajnadatta Sarangi and Ashok Kumar.
Author contributions: Sarangi Y did the literature search and wrote the manuscript; Kumar A designed the concept, revised and edited the manuscript; Sarangi Y and Kumar A contributed equally to this article, they are the co-first authors of this manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ashok Kumar, FACS, FASCRS, FRCS, FRCS (Ed), Full Professor, Professor, Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India.
Received: April 1, 2025
Revised: April 15, 2025
Accepted: June 3, 2025
Published online: July 24, 2025
Processing time: 115 Days and 23 Hours
Revised: April 15, 2025
Accepted: June 3, 2025
Published online: July 24, 2025
Processing time: 115 Days and 23 Hours
Core Tip
Core Tip: Gall bladder cancer is an aggressive disease with a dismal prognosis. Surgery offers the best treatment. However, most of the patients present late due to nonspecific symptoms and at a stage where resection is not feasible. Therefore, early detection is crucial for better outcomes. Identifying high-risk features, utilizing various imaging modalities, use of biomarkers, liquid biopsy and newer tools like artificial intelligence can aid in the early diagnosis.