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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Dec 24, 2025; 16(12): 103683
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.103683
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.103683
Stem cell collection from peripheral blood of multiple myeloma patients
Jonah Lee, Spencer Lee, Department of Radiation Oncology, Cancer Care Northwest, Spokane, WA 99204, United States
Quincy Seigel, Department of Internal Medicine, University of Texas Medical Branch at Galveston, Galveston, TX 77555, United States
Emily Green, College of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States
Sara Chitlik, College of Medicine, Rush Medical College, Chicago, IL 60612, United States
Veronika Lobova, General Surgery, UCSF Fresno Surgery, Fresno, CA 93701, United States
Paul Eastvold, Chris Gresens, Blood Center, Vitalant Blood Centers, Spokane, WA 99201, United States
Erin A Kaya, Department of Radiation Oncology, Oregon Health Sciences University, Portland, OR 97239, United States
Author contributions: Lee J data collection, data analysis, interpretation of results, writing manuscript; Seigel Q writing manuscript, critical review of data and manuscript; Lee S data analysis, writing manuscript; Green E critical review of data and manuscript; Chitlik S critical review of data and manuscript; Lobova V critical review of data and manuscript; Eastvold P project administration; Gresens C critical review of data and manuscript; Kaya EA supervision, visualization, critical review of data and manuscript.
Institutional review board statement: IRB review/approval was not required for this retrospective analysis due to only retrospectively analyzes patients' laboratory results.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: None of the authors have conflicts of interest to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Erin A Kaya, MD, Department of Radiation Oncology, Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239, United States.
Received: November 28, 2024
Revised: March 9, 2025
Accepted: November 14, 2025
Published online: December 24, 2025
Processing time: 391 Days and 13.3 Hours
Revised: March 9, 2025
Accepted: November 14, 2025
Published online: December 24, 2025
Processing time: 391 Days and 13.3 Hours
Core Tip
Core Tip: We are demonstrating a practical stem cell collection method that provides sufficient stem cells for autologous stem cell transplantation in multiple myeloma patients despite low peripheral CD34 (pCD34) counts and to describe the benefits of this method for patients with limited resources. We present three patients whose pre-collection pCD34 counts were less than 2.5 cells/μL and all successfully underwent stem cell collection in a single trip to the transplant center. This approach may benefit the high number of patients who face limited resources, finances, travel abilities, and social support.