ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role

doi:10.5306/wjco.v16.i11.110202

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 11

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (0)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-3) series, Tables (1-3) series.

Item

Count

PDF

HTML

Figures (1-3)

Tables (1-3)

Sum=0

Nov 24, 2025 (publication date) through Nov 21, 2025

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Clinical Oncology

ISSN

2218-4333

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Clin Oncol. Nov 24, 2025; 16(11): 110202
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.110202

ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role

Eva G Palacios Serrato, Karen H Medina-Abreu, Enrique Oropeza-Martínez, Luis Fernando Jacinto-Alemán, Marina Macías-Silva, Angeles C Tecalco-Cruz

Eva G Palacios Serrato, Karen H Medina-Abreu, Enrique Oropeza-Martínez, Angeles C Tecalco-Cruz, Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Mexico City 03100, Mexico

Luis Fernando Jacinto-Alemán, Departamento de Medicina y Patología, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico

Marina Macías-Silva, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico

Author contributions: Palacios Serrato EG researched, wrote, and integrated the information in the manuscript, tables, and figures; Medina-Abreu KH, Oropeza-Martínez E, and Jacinto-Alemán LF researched and wrote some parts of the manuscript and tables; Macías-Silva M participated in editing and improving the manuscript; Tecalco-Cruz AC designed this research, discussed, and integrated the manuscript; and all authors approved the final manuscript.

Supported by Colegio de Ciencia y Tecnologia de la Universidad Autónoma de la Ciudad de México, No. UACM- CCyT-2025-CON-11.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Angeles C Tecalco-Cruz, PhD, Full Professor, Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Colonia Del Valle, San Lorenzo 290, Mexico City 03100, Mexico. angeles.tecalco@uacm.edu.mx

Received: June 3, 2025
Revised: July 2, 2025
Accepted: October 10, 2025
Published online: November 24, 2025
Processing time: 174 Days and 9.6 Hours

Core Tip

Core Tip: In this article, we explore the published information on two proteases of the kallikrein family, kallikrein-related peptidases 5 and 10, and one metallopeptidase with a thrombospondin motif, ADAM metallopeptidase with thrombospondin type 1 motif 8, which are suggested to be both tumor suppressors and protumoral factors, depending on cancer context and stage.