©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Sep 24, 2024; 15(9): 1215-1221
Published online Sep 24, 2024. doi: 10.5306/wjco.v15.i9.1215
Published online Sep 24, 2024. doi: 10.5306/wjco.v15.i9.1215
Breast cancer and rectal cancer associated with Lynch syndrome: A case report
Pei-Fang Qin, Ling Yang, Jun-Ping Hu, Jing-Yue Zhang, Department of Laboratory Medicine, The People Hospital of Guigang, Guigang 537100, Guangxi Zhuang Autonomous Region, China
Co-first authors: Pei-Fang Qin and Ling Yang.
Author contributions: All authors contributed to the study conception and design; Qin PF and Yang L were responsible for analyzing data, material preparation, and writing the manuscript; Hu JP was responsible for drawing and data organization; Zhang JY directed the study and modified the article; all authors have read and approved the final manuscript.
Supported by The Natural Science Foundation from Guangxi , No. 2024GXNSFBA010056 ; The Guangxi Zhuang Autonomous Region Health Committee Self-Funded Scientific Research , No. Z-R20231938 ; and The Guangxi Medical University Youth Science Fund Project , No. GXMUYSF202333 .
Informed consent statement: The study according to the ethical guidelines of the Helsinki Declaration and was approved by the Human Ethics Committee of the people Hospital of Guigang. Written informed consent was obtained from individual or guardian participants.
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
CARE Checklist (2016) statement: The case has been written according to the CARE Checklist (2016).
Corresponding author: Jing-Yue Zhang, PhD, Doctor, Department of Laboratory Medicine, The People Hospital of Guigang, No. 1 Zhongshan Middle Road, Guigang 537100, Guangxi Zhuang Autonomous Region, China. zhangjy79@mail2.sysu.edu.cn
Received: February 4, 2024
Revised: July 28, 2024
Accepted: August 5, 2024
Published online: September 24, 2024
Processing time: 206 Days and 23.6 Hours
Revised: July 28, 2024
Accepted: August 5, 2024
Published online: September 24, 2024
Processing time: 206 Days and 23.6 Hours
Core Tip
Core Tip: Lynch syndrome (LS) is the most common hereditary cancer syndrome and is characterized by a predisposition to a range of cancers, mainly colorectal cancer and endometrial cancer. In this case, a patient suffered from breast cancer 10 years ago and was subsequently diagnosed with rectal cancer, which is different from traditional LS development. Developing methods to diagnosis LS patients and giving their relatives corresponding genetic counselling advice can significantly reduce the incidence of LS-related tumours.