Gao CF, Zhou P, Zhang C. Prenatal ultrasound diagnosis of fetal maxillofacial teratoma: Two case reports. World J Clin Oncol 2024; 15(9): 1245-1250 [PMID: 39351467 DOI: 10.5306/wjco.v15.i9.1245]
Corresponding Author of This Article
Chuan-Fen Gao, MD, Doctor, Department of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230022, Anhui Province, China. gaocf1032@163.com
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Oncol. Sep 24, 2024; 15(9): 1245-1250 Published online Sep 24, 2024. doi: 10.5306/wjco.v15.i9.1245
Prenatal ultrasound diagnosis of fetal maxillofacial teratoma: Two case reports
Chuan-Fen Gao, Pei Zhou, Chen Zhang
Chuan-Fen Gao, Department of Ultrasound, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Pei Zhou, Prenatal Diagnosis Center, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Chen Zhang, School of 1st Clinic Medicine, Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Gao CF contributed to study concept and design, data collection, drafting, reviewing, and editing of the manuscript; Zhou P contributed to consultation and specimen photo acquisition; Zhang C contributed to data analysis; Both authors have read and approved the final manuscript.
Supported bythe Research Fund of the Anhui Medical University, No. 2022xkj145.
Informed consent statement: Informed written consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chuan-Fen Gao, MD, Doctor, Department of Ultrasound, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230022, Anhui Province, China. gaocf1032@163.com
Received: May 17, 2024 Revised: July 25, 2024 Accepted: August 7, 2024 Published online: September 24, 2024 Processing time: 103 Days and 23.6 Hours
Abstract
BACKGROUND
Facial teratoma is a rare benign tumor that accounts for about 1.6% of all teratomas and can be diagnosed by prenatal ultrasound (US). The purpose of this report was to describe our experience with the diagnosis of fetal facial teratoma by prenatal US at second trimester to provide a reference for clinical diagnosis of fetal maxillofacial teratoma.
CASE SUMMARY
We present two cases of patients with abnormal fetal facial findings on US at second trimester of pregnancy in our department. Case 1 was a 31-year-old G3 P1 + 1 female, with US revealing a heterogeneous echogenicity of 32 mm × 20 mm × 31 mm on the fetal face, most of it located outside the oral cavity and filling the root of the oral cavity. Case 2 was a 29-year-old G1P0 female, with fetal head and neck US revealing a cystic-solid echo mass measuring 42 mm × 33 mm × 44 mm, the upper edge of the lesion reaching the palate and filling the oral cavity. The contours of the lesions were visualized using three-dimensional (3D) US imaging. Both patients decided to give up treatment. Biopsies of the lesions were performed after induction of labor, and diagnosed as maxillofacial teratoma.
CONCLUSION
Fetal maxillofacial teratomas can be diagnosed by US in early pregnancy, allowing parents to expedite treatment decisions.
Core Tip: Facial teratoma is a rare benign tumor that accounts for only about 1.6% of all teratomas and can be diagnosed by prenatal ultrasound (US). In this study, we presented two cases of pregnant women with prenatally diagnosed fetal maxillofacial teratomas by US. The study highlights the value of prenatal US in the identification of maxillofacial teratoma in early pregnancy and describes the ultrasonographic features of these tumors.
