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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pathophysiol. Dec 22, 2025; 16(4): 112536
Published online Dec 22, 2025. doi: 10.4291/wjgp.v16.i4.112536
Published online Dec 22, 2025. doi: 10.4291/wjgp.v16.i4.112536
Gastric motility and its association with adiposity and metabolic health in a cohort of Sri Lankan office workers
Pradeepa Isurumali Basnayake, Department of Physiology, Faculty of Medicine, Sabaragamuwa University of Sri Lanka, Ratnapura 70012, Sabaragamuwa Province, Sri Lanka
Dulani Kottahachchi, Kushan Medagoda, Niranga Manjuri Devanarayana, Department of Physiology, Faculty of Medicine, University of Kelaniya, Ragama 11010, Western Province, Sri Lanka
Dinu Santha Chandran, Department of Physiology, All India Institute of Medical Sciences, New Delhi 110029, India
Author contributions: Basnayake PI contributed to the study design, data collection, analysis, and interpretation of data, and wrote the initial draft; Kottahachchi D, Chandran DS, and Medagoda K helped study design and revised final manuscript; Devanarayana NM conceptualized the study and contributed to the study design, data collection (by conducting motility studies), interpretation of data, and writing and revising the manuscript; All authors approved the final version to be published.
Supported by the University of Kelaniya, Sri Lanka, Research Grant, No. RP/03/04/03/01/2022.
Institutional review board statement: This study was reviewed and approved by the Ethical Review Committee, Faculty of Medicine, University of Kelaniya, Sri Lanka (Ref. No: P/127/09/2022).
Informed consent statement: Written informed consent was obtained from each participant.
Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement - checklist of items, and the manuscript was prepared and revised according to the STROBE Statement - checklist of items.
Data sharing statement: The dataset is available from the corresponding author at niranga@kln.ac.lk. Participants provided informed consent for data sharing; however, the presented data are anonymized, and the risk of identification is considered low.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Niranga Manjuri Devanarayana, Professor, Department of Physiology, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama 11010, Western Pro
Received: July 30, 2025
Revised: August 13, 2025
Accepted: October 29, 2025
Published online: December 22, 2025
Processing time: 145 Days and 16.5 Hours
Revised: August 13, 2025
Accepted: October 29, 2025
Published online: December 22, 2025
Processing time: 145 Days and 16.5 Hours
Core Tip
Core Tip: This study investigated gastric motility in a cohort of Sri Lankan office workers, focusing on its associations with body mass index, adiposity, and metabolic indicators. Males showed significantly larger fasting antral areas, while in females, gastric motility was more closely linked to measures of adiposity and lipid profiles. These findings underscore the influence of metabolic status, particularly lipid metabolism, on gastric motor function, with notable sex-specific patterns. The results provide new insights into the potential impact of metabolic derangements on gastrointestinal physiology and support early identification of individuals at risk for motility disorders.