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Carbohydrate antigen 72-4 and tumor-associated glycoprotein 72 - tumor marker: Past, present and future
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World Journal of Gastrointestinal Pathophysiology is an international, peer-reviewed, open-access academic journal dedicated to publishing original, high-quality research findings in the field of gastrointestinal pathophysiology and liver physiology, including clinical, translational, and basic studies, as well as research involving artificial intelligence. The journal focuses on, but is not limited to, the following areas: Gastrointestinal pathophysiology (motility disorders, secretion and absorption, mucosal barrier and inflammation, neoplastic pathophysiology), liver physiology (metabolism, bile production, detoxification and drug metabolism, and liver regeneration), gut-liver axis, microbiome sciences, and neurogastroenterology. Types of articles published by the journal include clinical study, basic study, case report, editorial, review, minireview, systematic review, meta-analysis, guidelines, and correspondence. All submissions undergo a rigorous and transparent peer-review process by at least two independent reviewers. Manuscripts are evaluated based on scientific rigor, originality, clinical relevance, and reproducibility, with particular attention to methodological robustness and data integrity. Constructive and timely feedback is provided to ensure the highest standards of scholarly communication. The journal adheres to the highest standards of publication ethics and editorial integrity, in accordance with the guidelines of the Committee on Publication Ethics, the International Committee of Medical Journal Editors, and the World Association of Medical Editors. To advance scientific discovery, promote evidence-based clinical practice, and foster innovation in gastrointestinal pathophysiology, ultimately improving global health outcomes. We invite researchers, clinicians, and multidisciplinary experts worldwide to submit high-quality manuscripts and contribute to shaping the future of gastrointestinal pathophysiological science. Submit an Article >>

2026 Published Issues
3 2 1
Editors-in-Chief
  • Kusum K Kharbanda, PhD, Professor, (Email: kkharbanda@unmc.edu) Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68105, United States
  • Tsutomu Nishida, MD, PhD, (Email: tnishida@gh.med.osaka-u.ac.jp) Department of Gastroenterology, Toyonaka Municipal Hospital, Toyonaka, Osaka 560-8565, Japan
Indexing/Abstracting
The WJGP is now abstracted and indexed in PubMed, PubMed Central, Reference Citation Analysis, China Science and Technology Journal Database, and Superstar Journals Database.
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There is currently no impact factor.
ISSN
2150-5330 (online)
Latest Manuscript Statistics
Received (513), Duration of Peer Review (24 days/Mean), Days from Submission to First Decision (41 days/Mean), Second Decision Time (39 days/Mean), Accepted (56.5%/Mean), Production Time (55 days/Mean), Time to Publication (192 days/Mean), and Rejected (30.8%/Mean).
Current Issue
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Contents Volume 17 Issue 3 September 22, 2026
Field of Vision
Paradoxical nutrient hyperabsorption despite diarrhea: Insights from jejunal transcriptomic reanalysis in Linghu’s obesity-diarrhea syndrome
Xiao-Tong Niu, Xiang-Yao Wang, En-Qiang Linghu 
World J Gastrointest Pathophysiol 17(3):121798. Published online Sep 22, 2026. doi: 10.4291/wjgp.121798
Evidence Review
Microplastics and nanoplastics in inflammatory bowel disease: Mechanistic plausibility, human evidence and future research priorities
Richard Hall, Michael Colwill, Kamal Patel, Sailish Honap, Andrew Poullis 
World J Gastrointest Pathophysiol 17(3):122786. Published online Sep 22, 2026. doi: 10.4291/wjgp.122786
Minireviews
Cronkhite-Canada syndrome: An elusive gastrointestinal disorder with multisystem involvement-pathogenesis, diagnosis, and therapeutic strategies
Araj Naveed Siddiqui, Rabia Hafsa, Vikash Kumar Karmani, Zainab Rehan, Rishi Chowdhary 
World J Gastrointest Pathophysiol 17(3):121535. Published online Sep 22, 2026. doi: 10.4291/wjgp.121535
Advancing the understanding of eosinophilic esophagitis: From pathogenesis to novel therapies
Ashish Sharma, Angad Tiwari, Vishal Deshpande, Vishal Abhimutt Mahesh, Harendra Kumar, Anuj Shah, Ishita Ray, Rajvardhan Sisodia, Sneh Sonaiya, Saqr Alsakarneh, Hassam Ali, Dushyant Singh Dahiya 
World J Gastrointest Pathophysiol 17(3):121571. Published online Sep 22, 2026. doi: 10.4291/wjgp.121571
Pathophysiological management of gastric varices: From hemodynamics to targeted therapies
Suprabhat Giri, Ranjan K Patel, Tara Prasad Tripathy, Dibya Lochan Praharaj, Radhika Chavan 
World J Gastrointest Pathophysiol 17(3):122115. Published online Sep 22, 2026. doi: 10.4291/wjgp.122115
Intersections of gastrointestinal dysbiosis of the gut microbiome and aging
Sara Shu, Benjamin K P Woo 
World J Gastrointest Pathophysiol 17(3):124717. Published online Sep 22, 2026. doi: 10.4291/wjgp.124717
Carbohydrate antigen 72-4 and tumor-associated glycoprotein 72 - tumor marker: Past, present and future
Rui-Kyi Ng, Vishal G Shelat 
World J Gastrointest Pathophysiol 17(3):125464. Published online Sep 22, 2026. doi: 10.4291/wjgp.125464
Systematic Reviews
Accuracy of non-invasive tests for diagnosing liver fibrosis and steatosis: A systematic review
Saurin R Shukla, Mirza Amer Ali Baig, Arika Pareek, Namita Johari, Yeshika Thapa, Beulah Blessy Kumpati, Shreya Mahesh Nirmal, Ifrah Ayesha Imdad, Durnave Azid, Eniola Aina, Alisha Lakhani 
World J Gastrointest Pathophysiol 17(3):121790. Published online Sep 22, 2026. doi: 10.4291/wjgp.121790
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