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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pathophysiol. Sep 22, 2025; 16(3): 107273
Published online Sep 22, 2025. doi: 10.4291/wjgp.v16.i3.107273
Published online Sep 22, 2025. doi: 10.4291/wjgp.v16.i3.107273
Barrett’s esophagus: A review
Harleen Kaur Chela, Department of Gastroenterology and Hepatology, Charleston Area Medical Center, West Virginia University School of Medicine, West Virginia University School of Me
Mustafa Gandhi, Department of Gastroenterology and Hepatology, University of Missouri-Columbia, Columbia, MO 65211, United States
Mohammad Hazique, Department of Internal Medicine, University of Missouri-Columbia, Columbia, WV 65212, United States
Hamza Ertugrul, Department of Gastroenterology, West Virginia University Charleston Campus, Charleston, WV 25304, United States
Karthik Gangu, Department of Internal Medicine, Kansas University Medical Center, Kansas City, 66160, United States
Ebubekir Daglilar, Department of Gastroenterology and Hepatology, West Virginia University Charleston Campus, Charleston, WV 25303, United States
Author contributions: Kaur CH contributed to obtaining images for endoscopy and pathology; Karthik G contributed to created one of the images using software; Ebubekir D contributed to obtaining images for endoscopy, editing manuscript; Kaur CH, Karthik G, and Ebubekir D contributed to designed and outlined the study; Kaur CH, Mustafa G, and Hamza E contributed to literature review; Kaur CH, Mustafa G, Mohammad H, Hamza E, and Karthik G contributed to writing and editing the manuscript; All authors have contributed to the formulation of the manuscript.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Harleen Kaur Chela, Assistant Professor, Department of Gastroen
Received: March 20, 2025
Revised: April 30, 2025
Accepted: August 1, 2025
Published online: September 22, 2025
Processing time: 184 Days and 6.2 Hours
Revised: April 30, 2025
Accepted: August 1, 2025
Published online: September 22, 2025
Processing time: 184 Days and 6.2 Hours
Core Tip
Core Tip: Barrett’s esophagus is a clinical condition that is diagnosed endoscopically and is a premalignant condition. It involves the metaplastic transformation of the lining of the esophagus due to various risk factors. This review describes the pathogenesis as well as diagnosis and management.