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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Dec 28, 2025; 17(12): 114595
Published online Dec 28, 2025. doi: 10.4329/wjr.v17.i12.114595
Published online Dec 28, 2025. doi: 10.4329/wjr.v17.i12.114595
Developmental venous anomalies and cerebral cavernous malformations: Partners in crime
Nikolaos-Achilleas Arkoudis, Evgenia Efthymiou, Georgios Velonakis, Research Unit of Radio
Nikolaos-Achilleas Arkoudis, Evgenia Efthymiou, Dimitrios Chalmoukis, Anastasia Karachaliou, Andreas Papadopoulos, Spyridon Prountzos, Ornella Moschovaki-Zeiger, Olympia Papakonstantinou, Dimitrios Filippiadis, Georgios Velonakis, The Second Department of Radiology, General University Hospital “Attikon”, National and Kapodistrian University of Athens, Athens 12462, Greece
Manos Siderakis, Department of Radiology, Agios Savas Anticancer Hospital, Athens 11522, Greece
Ilianna Tsetsou, Department of Imaging and Interventional Radiology, “Sotiria” General and Chest Diseases Hospital of Athens, Athens 11527, Greece
George Triantafyllou, Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens 11527, Attikí, Greece
Nikolaos Gouliopoulos, Moorfields Eye Hospital, London 162, London, United Kingdom
Author contributions: Arkoudis NA, Siderakis M, Tsetsou I, Efthymiou E, Triantafyllou G, wrote the main manuscript text and prepared the figures. Chalmoukis D, Karachaliou A, Papadopoulos A, Prountzos S, Moschovaki-Zeiger O, assisted with conceptualization and prepared the figures and tables. Gouliopoulos N, Papakonstantinou O, Filippiadis D, Velonakis G assisted with conceptualization and provided supervision. All authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nikolaos-Achilleas Arkoudis, MD, PhD, Consultant, Lecturer, Re
Received: September 24, 2025
Revised: October 13, 2025
Accepted: November 3, 2025
Published online: December 28, 2025
Processing time: 93 Days and 23.1 Hours
Revised: October 13, 2025
Accepted: November 3, 2025
Published online: December 28, 2025
Processing time: 93 Days and 23.1 Hours
Core Tip
Core Tip: When developmental venous anomalies (DVAs) and cerebral cavernous malformations (CMs) coexist, the DVA’s altered venous pressure and flow can promote CM formation or rupture. Detecting a DVA next to an otherwise unexplained intracerebral hemorrhage can therefore raise suspicion of an occult CM as the underlying etiology. This finding can represent a clue that may be invaluable for daily clinical practice. This review aims to educate readers on the hallmark imaging ap