Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Dec 26, 2025; 17(12): 112141
Published online Dec 26, 2025. doi: 10.4330/wjc.v17.i12.112141
Published online Dec 26, 2025. doi: 10.4330/wjc.v17.i12.112141
Mild myocardial injury during percutaneous coronary intervention based on minor changes on electrocardiogram and heart rate variability
Illya A Chaikovsky, Dmytro O Dziuba, Оleg A Loskutov, Department of Anaesthesiology and Intensive Care, Shupyk National Healthcare University, Kyiv 04112, Ukraine
Illya A Chaikovsky, Department of Contactless Control Systems, V.M. Glushkov Institute of Cybernetics of the National Academy of Sciences, Kyiv 03187, Ukraine
Olga A Kryvova, Department of Medical Information Technologies, International Research and Training Center of the National Academy of Sciences, Kyiv 03187, Ukraine
Kyrylo S Malakhov, Microprocessor Technology Lab, V.M. Glushkov Institute of Cybernetics of the National Academy of Sciences, Kyiv 03187, Ukraine
Oleksandr P Romanchuk, Department of Internal and Family Medicine, Lesya Ukrainka Volyn National University, Lutsk 43025, Ukraine
Borys M Todurov, Department of Cardiosurgery, X-ray and Extracorporeal Technologies, Shupyk National Healthcare University, Kyiv 04112, Ukraine
Borys M Todurov, Department of Extracorporeal Methods of Treatment, Heart Institute Ministry of Health of Ukraine, Kyiv 02166, Ukraine
Оleg A Loskutov, Department of Anaesthesiology and Intensive Care for Infectious Diseases, Clinical Hospital No. 4, Kyiv 02000, Ukraine
Author contributions: Chaikovsky ІА, Dziuba DО, Todurov BM and Loskutov ОА conceptualized the study; Dziuba DО, Chaikovsky ІА developed the methodology of the study; Kryvova OA developed the software, provided the data visualization; Dziuba DО, Loskutov ОА validated the study, performed the investigation, implemented the data curation; Chaikovsky ІА, Kryvova OA performed the formal analysis of the study; Todurov BM provided the resources for the study; Chaikovsky ІА, Dziuba DО and Kryvova OA wrote the original draft of the manuscript; Chaikovsky ІА, Dziuba DО, Romanchuk OP, Malakhov KS performed review and editing of the subsequent versions; Loskutov ОА, Romanchuk OP supervised the study; Chaikovsky ІА, Dziuba DО and Malakhov KS conducted the project administration; all authors have read and agreed to the published version of the manuscript.
Supported by The National Research Foundation of Ukraine, No. 2023.04/0094
Institutional review board statement: The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of Shupik National Healthcare University of Ukraine.
Informed consent statement: Informed consent was obtained from all subjects involved in the study.
Conflict-of-interest statement: The authors declare no conflict of interest.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement- checklist of items.
Data sharing statement: All datasets generated for this study are included in the article/Supplementary material.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Oleksandr P Romanchuk, MD, PhD, Full Professor, Department of Internal and Family Medicine, Lesya Ukrainka Volyn National University, Bankova Street 9, Lutsk 43025, Ukraine. romanchuk.oleksandr@vnu.edu.ua
Received: July 23, 2025
Revised: August 13, 2025
Accepted: November 11, 2025
Published online: December 26, 2025
Processing time: 159 Days and 3 Hours
Revised: August 13, 2025
Accepted: November 11, 2025
Published online: December 26, 2025
Processing time: 159 Days and 3 Hours
Core Tip
Core Tip: The inherent invasiveness of percutaneous coronary intervention (PCI) introduces the risk of coronary vessel and myocardial damage. The aim of this study is to evaluate the utility of a novel electrocardiographic metric in detecting subtle myocardial injuries after coronary stenting. The study involved 23 patients who underwent PCI. A paired measurement approach was employed both before and several hours following the operation, using a proprietary electrocardiogram scoring system. The analysis delineated a distinct subgroup exhibiting significant myocardial damage post-stenting. The newly devised electrocardiographic metric proves to be a significant advancement in the early detection of myocardial damage following PCI.