Mesenteric Castleman disease: Two case reports and review of literature

Figure 1 Contrast-enhanced abdominal computed tomography scan. The axial view shows a 1.4 cm × 1.1 cm lymph node (yellow arrow) in the retroperitoneum.

Figure 2 Histopathological and immunohistochemical examinations. A: Scattered lymphoid follicles are formed. The follicular centers show proliferating small blood vessels with swollen endothelial cells and hyaline degeneration, surrounded by concentric layers of small lymphocytes (onion-skin layering). There is active proliferation of small vessels in the interfollicular areas (hematoxylin-eosin, × 20); B: CD20-positive B cells (× 20); C: CD21-positive highlighting follicular dendritic cell meshwork (× 20).