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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2026; 18(1): 112954
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.112954
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.112954
Clinical features of post-colonoscopy colorectal cancer and real-world multi-scale correlation analysis
Yuan Li, Chu-Yan Wang, Ya-Xin Li, Zhu-Jun Wu, Lin-Jie Guo, Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Co-first authors: Yuan Li and Chu-Yan Wang.
Author contributions: Li Y and Guo LJ participated in the literature search and study design; Li Y, Wang CY, and Guo LJ participated in the data analysis, data interpretation, writing, and critical revision; Li Y and Wang CY contributed equally to this article, they are the co-first authors of this manuscript; Li Y, Wang CY, Guo LJ, Li YX, and Wu ZJ participated in data collection; Li YX and Wu ZJ reviewed all the medical imaging, and prepared all the figures; and all authors reviewed the manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of West China Hospital, Sichuan University, No. 2025 (419).
Informed consent statement: Given the retrospective nature of the study, the Institutional Review Board granted a waiver for the requirement of informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lin-Jie Guo, MD, Associate Professor, Department of Gastroenterology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. guolj08@163.com
Received: August 15, 2025
Revised: September 12, 2025
Accepted: December 2, 2025
Published online: January 27, 2026
Processing time: 159 Days and 24 Hours
Revised: September 12, 2025
Accepted: December 2, 2025
Published online: January 27, 2026
Processing time: 159 Days and 24 Hours
Core Tip
Core Tip: The incidence of post-colonoscopy colorectal cancer (CRC) remains significant. Patients with advanced age or prior CRC surgical history are associated with an elevated risk of post-colonoscopy CRC and may warrant shorter surveillance intervals for follow-up colonoscopy. The proficiency of the endoscopist can also influence the incidence of post-colonoscopy CRC. Enhancing technical proficiency among endoscopists and prolonging withdrawal time during colonoscopy may reduce post-colonoscopy CRC risk.