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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2025; 17(11): 112182
Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.112182
Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.112182
Effectiveness of different appendiceal stump closure methods in laparoscopic appendectomy in children: A systematic review and network meta-analysis
Waleed A Elsayed, Department of Pediatric Surgery, King Fahd Hospital of University, Imam Abdulrahman bin Faisal University, Khobar 34447, Saudi Arabia
Sayed Ahmed Elhadi, Department of Pediatric Surgery, Faculty of Medicine, Al-Azhar University, Damietta 34511, Egypt
Dalia Gad, Hanan Mahmoud Mohamed, Department of Pediatric Surgery, Faculty of Medicine, Al-Azhar University, Cairo 11511, Egypt
Tarig Elsaid, Ahmed Elkhouly, Pediatric Surgery Department, Maternity and Children Hospital Tabuk, Saudi Arabia, Tabuk 43200, Saudi Arabia
Mahmoud Fahmy Omar, Department of Pediatric Surgery, Royal Commission Hospital, Al Jubayl 35417, Saudi Arabia
Ahmad Abdullah Almousa, Department of General Surgery, Royal Commission Hospital, Aljubail 35417, Saudi Arabia
Author contributions: All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Elsayed WA, Elhadi SA and Gad D; the first draft of the manuscript was written by Mohamed HM, Elsaid T, Omar MF, Almousa AA, Elkhouly A and all authors commented on previous versions of the manuscript; all authors read and approved the final manuscript
Conflict-of-interest statement: All the authors have no conflict of interest related to the manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Waleed A Elsayed, MD, Department of Pediatric Surgery, King Fahd Hospital of University, Imam Abdulrahman bin Faisal University, Building 3238, Muhamad Elyusuf Street, Khobar 34447, Saudi Arabia. wasayed@iau.edu.sa
Received: July 21, 2025
Revised: August 7, 2025
Accepted: September 18, 2025
Published online: November 27, 2025
Processing time: 128 Days and 23 Hours
Revised: August 7, 2025
Accepted: September 18, 2025
Published online: November 27, 2025
Processing time: 128 Days and 23 Hours
Core Tip
Core Tip: Laparoscopic appendectomy (LA) is the standard treatment for acute appendicitis in children, offering reduced postoperative pain and quicker recovery compared to open surgery. A critical aspect of LA is the secure closure of the appendiceal stump to avoid complications such as leakage and abscess formation. Various closure techniques are used, including endoloops, staplers, clips, and energy devices, but the optimal method remains unclear due to inconsistent evidence.