Review
Copyright ©The Author(s) 2025.
World J Diabetes. Mar 15, 2025; 16(3): 100329
Published online Mar 15, 2025. doi: 10.4239/wjd.v16.i3.100329
Figure 1
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Figure 1 Risk factors of diabetic foot ulcer.
Figure 2
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Figure 2 Pathophysiology of diabetic foot ulcer: Major factors involved in the pathogenesis of diabetic foot ulcers.
Figure 3
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Figure 3 Representation of Charcot foot entity.
Figure 4
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Figure 4 Underlying the pivotal function of the RANKL-OPG system in the development of deleterious bone changes is the pathophysiology of diabetic osteoarthropathy. PTH: Parathyroid hormone; AGE: Advanced glycation end product; PI3K: Phosphoinositide 3-kinase; PKC: Protein kinase C; CGRP: Calcitonin gene-related peptide.; RANKL: Receptor activator of nuclear factor-kappa B ligand; eNOS: Endothelial nitric oxide synthase; IL: Interleukin; OPG: Osteoprotegerin; RAGE: Receptor for advanced glycation end products; TNF: Tumour necrosis factor.