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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Feb 15, 2026; 17(2): 112856
Published online Feb 15, 2026. doi: 10.4239/wjd.v17.i2.112856
Published online Feb 15, 2026. doi: 10.4239/wjd.v17.i2.112856
Diabetes prolongs hospitalization and increases infection, cerebral edema, and neurological complications in meningioma patients: A retrospective study
Yu-Fu Zhang, Wei Ma, Long Chen, Shu-Kai Sun, Li Gao, Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi’an 710038, Shaanxi Province, China
Co-first authors: Yu-Fu Zhang and Wei Ma.
Author contributions: Zhang YF and Ma W have made equal contributions, including study design, data collection and analysis, and manuscript preparation as the co-first authors of this study; Zhang YF, Ma W and Gao L conducted the collation and statistical analysis, wrote the original manuscript and revised the paper; Chen L and Sun SK designed the experiments and conducted clinical data collection, performed postoperative follow-up and recorded the data; all authors read and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 82271453.
Institutional review board statement: This study was approved by the Ethics Committee of Tangdu Hospital, Fourth Military Medical University, No. K202507-07.
Informed consent statement: The ethics committee agrees to waive informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li Gao, PhD, Associate Chief Physician, Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, No. 569 Xinsi Road, Baqiao District, Xi’an 710038, Shaanxi Province, China. gaol089@yeah.net
Received: August 19, 2025
Revised: October 16, 2025
Accepted: December 23, 2025
Published online: February 15, 2026
Processing time: 171 Days and 1 Hours
Revised: October 16, 2025
Accepted: December 23, 2025
Published online: February 15, 2026
Processing time: 171 Days and 1 Hours
Core Tip
Core Tip: This retrospective study suggests that diabetes may be a significant modifier of recovery after meningioma surgery. Our findings indicate that patients with diabetes mellitus (DM) experienced higher rates of surgical site infection, clinically significant cerebral edema requiring intervention, prolonged hospitalization, and poorer long-term functional status. Furthermore, DM was associated with an increased risk of tumor recurrence and mortality in time-to-event analysis, suggesting a potential independent association. These results highlight the potential importance of recognizing DM as a key comorbidity that warrants careful perioperative management and vigilant long-term follow-up in this patient population.