Inhibiting exosomal miR-191 can induce ferroptosis in macrophages, thereby delaying the progression of colorectal cancer

doi:10.4251/wjgo.v18.i5.116881

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May 15, 2026 (publication date) through May 14, 2026

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World Journal of Gastrointestinal Oncology

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1948-5204

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 116881
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.116881

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Figure 1 Mechanism of action of exosomal miR-191 in colorectal cancer progression. This flowchart illustrates the role of exosomal miR-191 derived from colorectal cancer cells in promoting tumor progression by modulating macrophage function and the therapeutic effects of its inhibition. ROS: Reactive oxygen species; CRC: Colorectal cancer.

Citation: Wang ZW, Jia L, Qu LK, Gong GH. Inhibiting exosomal miR-191 can induce ferroptosis in macrophages, thereby delaying the progression of colorectal cancer. World J Gastrointest Oncol 2026; 18(5): 116881
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/116881.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.116881

Wang ZW, Jia L, Qu LK, Gong GH. Inhibiting exosomal miR-191 can induce ferroptosis in macrophages, thereby delaying the progression of colorectal cancer. World J Gastrointest Oncol 2026; 18(5): 116881 [DOI: 10.4251/wjgo.v18.i5.116881]

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