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World J Gastrointest Oncol. Mar 15, 2026; 18(3): 115737
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.115737
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.115737
Short- and long-term outcomes after endoscopic resection of sporadic nonampullary duodenal tumors: An 11-year single-center retrospective study
Hang Yu, Long Rong, Yun-Long Cai, Guan-Yi Liu, Xin-Yue Guo, Department of Endoscopy Center, Peking University First Hospital, Beijing 100034, China
Author contributions: Rong L conceiving and designing the study; Cai YL, Liu GY, Guo XY collecting the data; Cai YL, Liu GY, Guo XY analyzing and interpreting the data; Yu H writing the manuscript; Rong L providing critical revisions that are important for the intellectual content; all authors approving the final version of the manuscript.
Supported by National High Level Hospital Clinical Research Funding Interdepartmental Research Project of Peking University First Hospital, No. 2024IR01.
Institutional review board statement: The study complied with the Declaration of Helsinki and was approved by the Institutional Review Board of Peking University First Hospital (No. 2025110).
Informed consent statement: All participants provided written informed consent.
Conflict-of-interest statement: All authors declare that they have no conflict of interests.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at long-rongbjpek@hotmail.com. Participants gave informed consent for data sharing.
Corresponding author: Long Rong, Department of Endoscopy Center, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Received: October 31, 2025
Revised: December 17, 2025
Accepted: January 19, 2026
Published online: March 15, 2026
Processing time: 133 Days and 0.4 Hours
Revised: December 17, 2025
Accepted: January 19, 2026
Published online: March 15, 2026
Processing time: 133 Days and 0.4 Hours
Core Tip
Core Tip: Sporadic nonampullary duodenal tumors (SNADTs) are uncommon neoplasms in clinical practice. Endoscopic resection (ER) has become a widely adopted therapeutic modality for these lesions. Our study evaluates the outcomes of ER for nonampullay duodenal tumors to assess its efficacy and safety. ER for SNADTs is a safe and effective treatment strategy. Endoscopic therapy represents a viable first-line option for appropriately selected patients, offering favorable oncologic outcomes. Long-term follow-up and careful endoscopic surveillance are recommended to ensure early detection and management of potential recurrences.