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World J Gastrointest Oncol. Feb 15, 2026; 18(2): 113508
Published online Feb 15, 2026. doi: 10.4251/wjgo.v18.i2.113508
Frequency and characteristics of synchronous gastric cancers: Need for improved awareness and better detection
Amit Kumar Dutta, Nicholas Vijay Rao, Pegatraju Krishna Bharadwaj, Stephan Benny
Amit Kumar Dutta, Nicholas Vijay Rao, Pegatraju Krishna Bharadwaj, Stephan Benny, Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India
Author contributions: Dutta AK conceived the review and wrote the manuscript; Dutta AK, Rao NV, Bharadwaj PK, and Benny S did the literature review and critically reviewed the manuscript. All authors approved the final version to publish.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amit Kumar Dutta, FRCPE, Professor, Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Ground Floor, Williams Building, Vellore 632004, Tamil Nadu, India. akdutta1995@yahoo.co.in
Received: August 27, 2025
Revised: September 11, 2025
Accepted: December 10, 2025
Published online: February 15, 2026
Processing time: 160 Days and 12 Hours
Core Tip

Core Tip: Gastric cancer is among the top causes of cancer globally. Approximately one in ten patients with gastric cancer has a coexisting neoplastic lesion in the stomach. In most instances, these synchronous lesions are at an early and curable stage. However, one-third of them are not detected at the time of diagnosis of the primary cancer. This can adversely affect the overall outcome. This minireview highlights the characteristics and risk factors of synchronous gastric neoplasms. Advances in endoscopic techniques, such as magnification and digital chromoendoscopy, facilitate better visualisation of gastrointestinal mucosa and detection of lesions. Utilization of these techniques and improved awareness about synchronous lesions may improve the detection rate and clinical outcome.