Rectal neuroendocrine tumors: Update

doi:10.4251/wjgo.v18.i1.114818

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 1

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (11)

All Articles published online

The chart showing PDF series, HTML series, Tables (1-2) series.

Item

Count

PDF

HTML

Tables (1-2)

Sum=29

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=12

Jan 15, 2026 (publication date) through Jan 12, 2026

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Oncology

ISSN

1948-5204

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Gastrointest Oncol. Jan 15, 2026; 18(1): 114818
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.114818

Rectal neuroendocrine tumors: Update

Mohammed Khayyat, Yasir M Khayyat

Mohammed Khayyat, King Abdulaziz University College of Medicine, King Abdulaziz University Hospital, Jeddah 214455, Saudi Arabia

Yasir M Khayyat, Department of Medicine, Faculty of Medicine, Umm AL-Qura University, Makkah 8156-24381, Saudi Arabia

Author contributions: Khayyat M performed literature review, collection and Khayyat YM performed initial drafting and final review of the manuscript.

Conflict-of-interest statement: Both authors have nothing to disclose.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Yasir M Khayyat, Professor, Department of Medicine, Faculty of Medicine, Umm AL-Qura University, AlAwali District, Makkah 8156-24381, Saudi Arabia. ymkhayyat@uqu.edu.sa

Received: September 29, 2025
Revised: October 11, 2025
Accepted: November 18, 2025
Published online: January 15, 2026
Processing time: 105 Days and 18.5 Hours

Core Tip

Core Tip: This manuscript highlights that, although rare, rectal neuroendocrine tumors exhibit distinct prognostic and therapeutic profiles. Key innovations include the identification of metabolic syndrome components as risk factors, the prognostic value of vascular patterns and biomarkers such as chromogranin A as well as the refined endoscopic resection techniques showing efficacy for small tumors. Importantly, tumor grade and size are critical for predicting metastasis and survival, and local excision is often sufficient for smaller lesions.