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Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2026; 18(1): 113662
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.113662
Combined multidetector computed tomography and gastrointestinal endoscopy for gastric cancer screening, preoperative staging, and lymph node metastasis detection
Le-Ping Ye, Yan-Ping Zhang, Gang Chen, Yi-Xian Wu, Cheng-Long He, Dong Wang, Qiao Mei
Le-Ping Ye, Qiao Mei, Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Le-Ping Ye, Yan-Ping Zhang, Gang Chen, Yi-Xian Wu, Department of Gastroenterology, Anqing Municipal Hospital, Anqing 246003, Anhui Province, China
Cheng-Long He, Department of General Surgery, Anqing Municipal Hospital, Anqing 246003, Anhui Province, China
Dong Wang, Department of Medical Imaging, Anqing Municipal Hospital, Anqing 246003, Anhui Province, China
Author contributions: Ye LP was responsible for the study design, data collection, and manuscript drafting; Zhang YP performed the data analysis and interpretation; Chen G, Wu YX, He CL, and Wang D participated in patient recruitment, clinical evaluation, and data curation; Mei Q supervised the entire research project and provided critical revisions to the manuscript. All authors read and approved the final version for submission.
Institutional review board statement: The procedures for both T1 and T2 surveys adhered to the Declaration of Helsinki, and ethical principles for medical, psychological, and sociological research involving human participants. The Anqing Municipal Hospital Research Ethics Committee approved the study protocol.
Informed consent statement: All individuals who participated in this study provided their written informed consent prior to study enrolment.
Conflict-of-interest statement: The authors declares that they have no conflicts of interest to report regarding the present study.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiao Mei, MD, Chief Physician, Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230022, Anhui Province, China. meiqiao@hotmail.com
Received: September 1, 2025
Revised: September 29, 2025
Accepted: November 14, 2025
Published online: January 15, 2026
Processing time: 134 Days and 18.2 Hours
Core Tip

Core Tip: Combining multidetector computed tomography and gastrointestinal endoscopy significantly improved diagnostic performance for gastric cancer screening, preoperative T and N staging, and lymph node metastasis detection compared with either modality alone. The combined approach demonstrated superior sensitivity, specificity, and accuracy, offering greater concordance with postoperative pathological findings. This integrative strategy supports more informed clinical decision-making and optimized preoperative planning.