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Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Sep 15, 2025; 17(9): 106912
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.106912
Investigation of gastrointestinal tumor symptoms and risk factors in eighty patients with Parkinson’s disease
Zhong-Guo Fu, Zhan-Xiu Ren, Xin-Hong Wang, Bai-Fang Wang
Zhong-Guo Fu, Department of Neurology, The First People’s Hospital of Shenyang, Shenyang 110041, Liaoning Province, China
Zhan-Xiu Ren, Department of Neurology, The People’s Hospital of Liaoning Province, Shenyang 110041, Liaoning Province, China
Xin-Hong Wang, Department of Neurology, General Hospital of Northern Theatre Command, Shenyang 110041, Liaoning Province, China
Bai-Fang Wang, Department of Endoscopy, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang 110041, Liaoning Province, China
Author contributions: Fu ZG designed the study and was involved in data collection and manuscript preparation; Fu ZG, Ren ZX, Wang XH, and Wang BF contributed to the review of the manuscript; and all authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the First People’s Hospital of Shenyang, China.
Informed consent statement: All study participants and their legal guardians provided written informed consent before enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhong-Guo Fu, PhD, Department of Neurology, The First People’s Hospital of Shenyang, No. 67 Qingquan Road, Dadong District, Shenyang 110041, Liaoning Province, China. fzg15940517539@126.com
Received: May 9, 2025
Revised: June 6, 2025
Accepted: August 4, 2025
Published online: September 15, 2025
Processing time: 128 Days and 18.2 Hours
Core Tip

Core Tip: This study investigated 80 patients diagnosed with Parkinson’s disease and revealed that approximately 20% of them had coexisting gastrointestinal tumors. Common symptoms included constipation and urgent bowel movements. The presence of tumors was significantly associated with factors such as sex, disease duration, gastrointestinal function scores, and elevated levels of multiple tumor markers, offering insight into early identification of high-risk patients.