©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2026; 18(2): 115174
Published online Feb 16, 2026. doi: 10.4253/wjge.v18.i2.115174
Published online Feb 16, 2026. doi: 10.4253/wjge.v18.i2.115174
Pretraction-assisted endoscopic submucosal dissection for rectal neuroendocrine tumors: Efficacy and future directions
Hua-Yu Dai, Xiao Liang, Yi-Qing Zhu, Zhen Li, Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
Author contributions: Dai HY wrote the original draft; Liang X, Zhu YQ, and Li Z contributed to writing, reviewing, and editing; Dai HY, Liang X, Zhu YQ, and Li Z participated in drafting the manuscript; Li Z contributed to conceptualization; and all authors have read and approved the final version of the manuscript.
Supported by the Taishan Scholars Program of Shandong Province, No. tsqn202306344.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Zhen Li, MD, Chief Physician, Professor, Department of Gastro
Received: October 14, 2025
Revised: November 18, 2025
Accepted: December 19, 2025
Published online: February 16, 2026
Processing time: 116 Days and 3.3 Hours
Revised: November 18, 2025
Accepted: December 19, 2025
Published online: February 16, 2026
Processing time: 116 Days and 3.3 Hours
Core Tip
Core Tip: Pretraction-assisted endoscopic submucosal dissection is a safe and effective therapeutic technique for rectal neuroendocrine tumors. This significantly improves R0 resection rates and reduces the risk of adverse events. Further validation of the efficacy and generalizability of pretraction-assisted endoscopic submucosal dissection requires elucidating its specific mechanisms, conducting prospective multicenter studies, and performing long-term follow-up.