Ginger mitigates acrylamide-induced hepatotoxicity through antioxidant and anti-inflammatory mechanisms in rats

Table 1 mean ± SD of biochemical parameters in different groups

Parameter	Normal control (I) (n = 10)	Ginger treated group (II) (n = 10)	ACR treated group (III) (n = 10)	ACR + ginger treated group (IV) (n = 10)
Alanine aminotransferase (IU/L)	19.90 ± 2.46	21.10 ± 3.44	104.30 ± 14.29	57.10 ± 9.51
Aspartate aminotransferase (IU/L)	35.10 ± 4.01	31.00 ± 2.98	90.80 ± 6.89	57.70 ± 6.66
Alkaline phosphatase (IU/L)	93.30 ± 4.39	91.90 ± 3.21	162.70 ± 8.00	118.90 ± 6.82
Malondialdehyde (nmol/mL)	5.22 ± 0.65	4.59 ± 0.35	20.02 ± 1.90	8.41 ± 1.24
Glutathione (μ/mL)	32.10 ± 2.39	35.30 ± 3.56	18.40 ± 2.59	22.90 ± 1.91
Catalase (μmol/second/mL)	13.21 ± 0.86	14.77 ± 1.16	6.97 ± 0.92	10.40 ± 0.89
Superoxide dismutase (μ/mL)	168.70 ± 5.90	201.70 ± 11.76	128.00 ± 7.34	144.20 ± 5.15

Table 2 One-way analysis of variance test results

Parameter	F value	P value
Alanine aminotransferase (IU/L)	202.01	< 0.001
Aspartate aminotransferase (IU/L)	256.92	< 0.001
Alkaline phosphatase (IU/L)	312.21	< 0.001
Malondialdehyde (nmol/mL)	358.42	< 0.001
Glutathione (μ/mL)	86.01	< 0.001
Catalase (μmol/second/mL)	124.41	< 0.001
Superoxide dismutase (μ/mL)	162.03	< 0.001