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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Hepatol. Jun 27, 2026; 18(6): 120789
Published online Jun 27, 2026. doi: 10.4254/wjh.120789
Protective effects of kaempferol against diet-induced metabolic disorders
Vinesh Sharma, Vikram Patial
Vinesh Sharma, Vikram Patial, Dietetics and Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, Himachal Pradesh, India
Vinesh Sharma, Vikram Patial, Academy of Scientific and Innovative Research, Ghaziabad 201002, India
Author contributions: Sharma V conducted the literature review and prepared the manuscript; Patial V contributed to the study design, manuscript writing, and editing. Both authors have read and approved the final version of the manuscript (No. 6095).
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Vikram Patial, PhD, Principal Scientist, Dietetics and Nutrition Technology Division, CSIR-Institute of Himalayan Bioresource Technology, No. 6 Post Box, Palampur 176061, Himachal Pradesh, India. vikram.patial@csir.res.in
Received: March 9, 2026
Revised: March 29, 2026
Accepted: June 2, 2026
Published online: June 27, 2026
Processing time: 106 Days and 8.9 Hours
Core Tip

Core Tip: The increasing prevalence of obesity and metabolic dysfunction-associated steatotic liver disease in the Indian population is closely linked to high-fat, high-sugar dietary patterns and a sedentary lifestyle. Developing region-specific dietary models can aid in effective preclinical screening of therapeutic agents. In this context, Kaempferol, a natural flavonoid with antioxidant, anti-inflammatory, and lipid-regulating properties, shows promising potential as a nutraceutical strategy for the management of metabolic dysfunction-associated steatotic liver disease.

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