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Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 27, 2025; 17(12): 111425
Published online Dec 27, 2025. doi: 10.4254/wjh.v17.i12.111425
Performance of artificial intelligence in predicting hepatocellular carcinoma recurrence after thermal ablation: A systematic review
Alessandro Posa, Marcello Lippi, Pierluigi Barbieri, Edoardo Vincenzo Andreani, Roberto Iezzi
Alessandro Posa, Marcello Lippi, Pierluigi Barbieri, Edoardo Vincenzo Andreani, Roberto Iezzi, Department of Diagnostic Imaging and Radiation Oncology, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome 00168, Lazio, Italy
Author contributions: Posa A, Lippi M and Barbieri P designed the study, analyzed the data and prepared the original draft; Posa A, Lippi M, Barbieri P, Andreani EV and Iezzi R reviewed and edited the draft; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Alessandro Posa, MD, Department of Diagnostic Imaging and Radiation Oncology, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Largo Agostino Gemelli 8, Rome 00168, Lazio, Italy. alessandro.posa@policlinicogemelli.it
Received: June 30, 2025
Revised: August 20, 2025
Accepted: November 13, 2025
Published online: December 27, 2025
Processing time: 180 Days and 13.6 Hours
Core Tip

Core Tip: Artificial intelligence can aid the prediction of post-thermal ablation treatment recurrence of hepatocellular carcinoma, improving patient's quality of life, tailoring the follow-up and avoiding unnecessary treatments while providing an early recognition of tumor recurrence.